{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T21:40:48Z","timestamp":1784842848507,"version":"3.55.0"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,5,19]],"date-time":"2024-05-19T00:00:00Z","timestamp":1716076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Given the paucity of data, the objective of this study is to evaluate the association between obesity and major wound complications following pelvic bone sarcoma surgery specifically.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent pelvic resection for bone sarcoma from 2005 to 2021 with a minimum 6\u2010month follow\u2010up were reviewed. Patients with benign tumors, primary soft tissue sarcomas, local recurrence at presentation, pelvic metastatic disease, and underweight patients were excluded. A major wound complication was defined as the need for a secondary debridement procedure. Differences in baseline demographics, surgical factors, postoperative complications, and functional outcomes were compared between obese and nonobese patients. A multivariate logistic regression was performed to identify independent risk factors for major wound complications, and a Kaplan\u2013Meier analysis to estimate overall survival between both groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 93 included patients, 21 were obese (body mass index\u2009\u2265\u200930\u2009kg\/m<jats:sup>2<\/jats:sup>). The obesity group had a significantly higher rate of major wound complication (52% vs. 26%, <jats:italic>p<\/jats:italic>\u2009=\u20090.034) and a lower Toronto Extremity Salvage Score at 1\u2010year postoperatively (47.5 vs. 71.4, <jats:italic>p<\/jats:italic>\u2009=\u20090.025). Obesity was the only independent risk factor in the multivariate analysis. No differences in overall survival were demonstrated between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Obesity is a significant risk factor for major wound complications in pelvic bone sarcoma treatment. This highlights the importance of careful perioperative optimization and wound management.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.27690","type":"journal-article","created":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T01:43:22Z","timestamp":1716169402000},"page":"293-300","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Obesity increases the risk of major wound complications following pelvic resection for bone sarcoma"],"prefix":"10.1002","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7015-3286","authenticated-orcid":false,"given":"Patrick Qi","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Surgery University of Toronto Toronto Ontario Canada"},{"name":"Department of Surgery, Sinai Health System, Mount Sinai Hospital, Division of Orthopaedic Surgery University of Toronto Musculoskeletal Oncology Unit Toronto Ontario 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