{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T22:41:05Z","timestamp":1783982465509,"version":"3.55.0"},"reference-count":44,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T00:00:00Z","timestamp":1732147200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Prospective data on presentation and outcomes of colorectal cancer (CRC) in Nigeria are limited; however, emergency presentation with advanced disease is thought common.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive CRC patients presenting at six sites over 6 years were included. Risk factors for emergency presentation were evaluated using logistic regression methods. Overall survival (OS) was compared between emergent and elective patients using Kaplan\u2010Meier methods and the log\u2010rank test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 535 patients, 30.7% presented emergently. Median age was 56 years, 55% were men, and 5.0% reported a cancer family history. Emergency patients had more proximal cancers (42.1% vs. 24.0%), Stage IV disease (61.6% vs. 40.2%; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), lower household income (\u20a635\u2009000\/month vs. \u20a650\u2009000\/month), lower education levels (<jats:italic>p<\/jats:italic>\u2009=\u20090.008) and accessed care with nonmotorized transport (50.6% vs. 37.2%; <jats:italic>p<\/jats:italic>\u2009=\u20090.005). Median OS was shorter in the emergency group (6.4 vs. 17.4 months; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Across clinical stages, emergency presentation was associated with worse OS (Stage IV median OS 4.8 vs. 9.4 months; <jats:italic>p<\/jats:italic>\u2009=\u20090.002). Surgery improved survival in both groups, although emergency patients had higher 30\u2010day postoperative mortality (23.2% vs. 9.1%; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Emergent Nigerian CRC patients have worse OS than elective patients. Cancer control efforts should focus on faster cancer detection, early presentation, diagnosis, and treatment.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.27878","type":"journal-article","created":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T08:16:26Z","timestamp":1732263386000},"page":"170-182","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Analysis of Risk Factors, Treatment Patterns, and Survival Outcomes After Emergency Presentation With Colorectal Cancer: A Prospective Multicenter Cohort Study in Nigeria"],"prefix":"10.1002","volume":"131","author":[{"given":"Adeniyi S.","family":"Aderibigbe","sequence":"first","affiliation":[{"name":"Department of Surgery Federal Medical Center Owo Ondo State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna J.","family":"Dare","sequence":"additional","affiliation":[{"name":"Department of Surgery St. Michael's Hospital &amp; University of Toronto Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah L.","family":"Kalvin","sequence":"additional","affiliation":[{"name":"Department of Epidemiology &amp; 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