{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T23:11:01Z","timestamp":1781910661618,"version":"3.54.5"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T00:00:00Z","timestamp":1726704000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Peritoneal metastasis (PM) is a common evolution of abdominal tumors. Without aggressive multimodal treatment, it is associated with a poor prognosis. The aim of this study is to present a multicenter results from Saudi Arabia on minimally invasive CRS and HIIPEC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis of a prospective maintained multicenter database was queried for all patients treated with laparoscopic or robotic CRS and HIPEC between 2019 and 2024 in Saudi Arabia. Surgical and oncological outcome was analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eleven consecutive patients underwent minimally invasive CRS and HIPEC between 2019 and 2024. Eight patients (72.7%) were operated by laparoscopy, one of them by single port access and three patients (27.3%) were operated robotically. Six patients (54.5%) were female. Median age was 42 (29\u201364). Primary tumor was PMP from the appendix, colon, and MCM in 6 (54.5%), 4 (36.4%), and 1 (9.1%) respectively. The median duration to complete the surgical procedure for all patients was 330 (230\u2013580) min and for robotic CRS the median docking time was 570 (330\u2013580) min. Median PCI was 2 (1\u20137) and completeness Cytoreduction (CC score 0) was achieved in the all patients (100%). Median hospital stay was 8 days (3\u201320). Four patients had one night postoperative ICU stay. Major morbidity (CTCAE) 3 and 4 occurred in three patients (27.3%) (Port site hernia, bleeding, and wound infection). No readmission to the hospital and no 90 days mortalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The minimally invasive approach by laparoscopy or robot is a feasible and promising option for CRS and HIPEC. It reduces the hospital stay, early return to intended oncological treatment (RIOT). Further prospective clinical studies are needed to evaluate this approach.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.27902","type":"journal-article","created":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T08:26:02Z","timestamp":1726734362000},"page":"1326-1331","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Robotic and Laparoscopic Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy, Multicenter Study From Saudi Arabia"],"prefix":"10.1002","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0040-8511","authenticated-orcid":false,"given":"Mohammad","family":"Alyami","sequence":"first","affiliation":[{"name":"Department of General Surgery and Surgical Oncology Oncology Center, King Khalid Hospital Najran Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah Muhammed","family":"Abdulrahem","sequence":"additional","affiliation":[{"name":"Department of General Surgery and Surgical Oncology Oncology Center, King Khalid Hospital Najran Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mashhour","family":"Alqannas","sequence":"additional","affiliation":[{"name":"Department of General Surgery and Surgical Oncology Oncology Center, King Khalid Hospital Najran Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hessa","family":"AlHabes","sequence":"additional","affiliation":[{"name":"Department of General Surgery and Surgical Oncology Oncology Center, King Khalid Hospital Najran Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Awad","family":"Alyami","sequence":"additional","affiliation":[{"name":"Department of General Surgery and Surgical Oncology Oncology Center, King Khalid Hospital Najran Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sulaiman","family":"Alshammari","sequence":"additional","affiliation":[{"name":"Department of Surgery, College of Medicine, King Khalid University Hospital King Saud University Medical City Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3834-2271","authenticated-orcid":false,"given":"Delia Cortes","family":"Guiral","sequence":"additional","affiliation":[{"name":"Department of General Surgery and Surgical Oncology Oncology Center, King Khalid Hospital Najran Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahdi","family":"Alzamanan","sequence":"additional","affiliation":[{"name":"Department of General Surgery and Surgical Oncology Oncology Center, King Khalid Hospital Najran Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0150-8338","authenticated-orcid":false,"given":"Nayef","family":"Alzahrani","sequence":"additional","affiliation":[{"name":"Department of Surgery King Abdulaziz Medical City, Ministry of National Guard Health Affairs Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thamer","family":"Bin Traiki","sequence":"additional","affiliation":[{"name":"Department of Surgery, College of Medicine, King Khalid University Hospital King Saud University Medical City Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(20000115)88:2<358::AID-CNCR16>3.0.CO;2-O"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.39.7166"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.23.9640"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010015\u20105081\u20103"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31827e9289"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1708618"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-021-00326-6"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-022-00675-5"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(20)30599-4"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31820784df"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-019-07280-1"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-018-6352-4"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2020.11.140"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4613-1247-5_23"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/00031348231161709"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2016.03.015"},{"key":"e_1_2_9_18_1","unstructured":"National Cancer Institute. Cancer Therapy Evaluation Program. Common Terminology Criteria For Adverse Events v4.0 (CTCAE) (2010).http:\/\/ctep.cancer.gov\/protocolDevelopment\/electronic_applications\/ctc.htm."},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2023.107001"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/gastro\/goae001"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-019-07349-x"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-022-09589-w"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15010279"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2014.11.008"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10723"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2019.12.006"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15617"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11701-018-0820-7"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.27902","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T05:33:23Z","timestamp":1739511203000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.27902"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,19]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1002\/jso.27902"],"URL":"https:\/\/doi.org\/10.1002\/jso.27902","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,19]]},"assertion":[{"value":"2024-08-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}