{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T15:23:23Z","timestamp":1784647403285,"version":"3.55.0"},"reference-count":178,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T00:00:00Z","timestamp":1732147200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients in low\u2010 and middle\u2010income countries (LMICs) are disproportionately affected by liver cancers but there is a lack of understanding of their postoperative outcomes. This study aimed to review the current status of research in LMICs regarding outcomes after oncologic hepatectomy and synthesize the data reported in the literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The PubMed, Scopus, Embase, Web of Science, and World Health Organization (WHO) Global Index Medicus databases were searched from database inception to May 26th, 2022. Studies that reported outcomes after oncologic hepatectomy in LMIC settings were eligible for inclusion. Two independent reviewers performed record screening and data extraction. Risk of bias assessment was performed using the National Institutes of Health Study Quality Assessment tools. Pooled results with 95% confidence intervals (95% CIs) were calculated using a random effects model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>One hundred and thirty\u2010five studies and 16\u2009985 patients were included. Most studies were of a \u201cfair\u201d quality. Two studies described pediatric patients. Only one study was from a low\u2010income country and most African regions were not represented. The rates of major and minor complications were 11% and 27%, respectively, while 30\u2010 and 90\u2010day mortality rates were 2% and 3% each. Postoperative liver failure (8%), surgical site infections (6%), and bile leaks (6%) were common complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This review indicates a dearth of data from LMICs on outcomes after hepatectomy, particularly from African regions and low\u2010income countries.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jso.27928","type":"journal-article","created":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T01:56:50Z","timestamp":1732240610000},"page":"865-878","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A Systematic Review and Meta\u2010Analysis of Oncologic Liver Resections in Low\u2010 and Middle\u2010Income Countries: Opportunities to Improve Evidence and Outcomes"],"prefix":"10.1002","volume":"131","author":[{"given":"Adel H.","family":"Khan","sequence":"first","affiliation":[{"name":"Khyber Medical College Peshawar Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6514-1646","authenticated-orcid":false,"given":"Omar","family":"Mahmud","sequence":"additional","affiliation":[{"name":"Medical College, Aga Khan University Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asad Saulat","family":"Fatimi","sequence":"additional","affiliation":[{"name":"Medical College, Aga Khan University Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaheer","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Islamabad Medical and Dental College Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6101-8138","authenticated-orcid":false,"given":"Alyssa A.","family":"Wiener","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Wisconsin School of Medicine and Public Health Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhuri V.","family":"Nishtala","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Wisconsin School of Medicine and Public Health Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher C.","family":"Stahl","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Wisconsin School of Medicine and Public Health Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie","family":"Christensen","sequence":"additional","affiliation":[{"name":"Ebling Library University of Wisconsin Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Rizwan","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Surgery Aga Khan University Hospital Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick B.","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Wisconsin School of Medicine and Public Health Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Nabeel","family":"Zafar","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Wisconsin School of Medicine and Public Health Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,21]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"\u201cCancer Today \u201d accessed October 25 2023 https:\/\/gco.iarc.fr\/today\/home."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/EDBK_200939"},{"key":"e_1_2_10_4_1","unstructured":"\u201cAmerican Cancer Society \u201d What Is Liver Cancer? 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