{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T22:20:00Z","timestamp":1778624400391,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T00:00:00Z","timestamp":1727827200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS\/HIPEC) can be associated with prolonged hospital stays. A novel Enhanced Recovery After Surgery (ERAS) based on ERAS Society guidelines was designed and implemented. The primary outcome was ERAS compliance. Secondary outcomes included length of stay (LOS) and postoperative complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A retrospective study on patients who underwent CRS\/HIPEC between 2018 and 2022, with ERAS implementation in 2022. Health records were reviewed. Statistical analysis included descriptive statistics, Wilcoxon tests, Student\n                      <jats:italic>t<\/jats:italic>\n                      \u2010test, and\n                      <jats:italic>\u03c7<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      and binomial negative regression. Health Ethics Research Board approval was obtained.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Eighty patients underwent CRS\/HIPEC: 59 in the pre\u2010ERAS group and 21 in the post\u2010ERAS group. Groups were similar in age, comorbidities, and Peritoneal Carcinomatosis Index. ERAS compliance increased from 32.8% to 70.8% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Median LOS decreased from 14 to 9 days (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Comparing pre\u2010ERAS to post\u2010ERAS showed no significant difference in the major morbidity rate (13.6% vs. 9.5%) or 30\u2010day readmission (9.4% vs. 4.8%) and no mortalities. Controlling for patient characteristics, the mean LOS decreased by 6.94 days (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Implementation of an ERAS CRS\/HIPEC program is safe and allows for improved compliance to ERAS protocols and a significant reduction in LOS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jso.27931","type":"journal-article","created":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T02:45:18Z","timestamp":1727923518000},"page":"527-534","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Implementation of a Multidisciplinary Enhanced Recovery After Surgery (ERAS) Program for Cytoreductive Surgery (CRS) With Hyperthermic Intraperitoneal Chemotherapy (HIPEC)"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8245-1013","authenticated-orcid":false,"given":"Cecily","family":"Stockley","sequence":"first","affiliation":[{"name":"Department of Surgery and Oncology University of Calgary Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9399-8372","authenticated-orcid":false,"given":"Antoine","family":"Bouchard\u2010Fortier","sequence":"additional","affiliation":[{"name":"Department of Surgery and Oncology University of Calgary Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0742-3861","authenticated-orcid":false,"given":"Jennifer","family":"Mateshaytis","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Calgary Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2855-5919","authenticated-orcid":false,"given":"Kadhim","family":"Taqi","sequence":"additional","affiliation":[{"name":"Department of Surgery and Oncology University of Calgary Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lloyd","family":"Mack","sequence":"additional","affiliation":[{"name":"Department of Surgery and Oncology University of Calgary Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8177-1098","authenticated-orcid":false,"given":"Gregg","family":"Nelson","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Calgary Calgary Alberta Canada"},{"name":"Ariadne Labs, Brigham and Women's Hospital, Harvard T.H. Chan School of Public Health Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Chong","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology University of Calgary Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1768-263X","authenticated-orcid":false,"given":"Melina","family":"Deban","sequence":"additional","affiliation":[{"name":"Department of Surgery and Oncology University of Calgary Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10,2]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2016.4952"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2023.04.009"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-020-05462-w"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-018-4844-y"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-021-06394-9"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.17310"},{"issue":"1","key":"e_1_2_10_8_1","first-page":"143","article-title":"Cytoreductive Surgery and Intraperitoneal Chemotherapy: An Evidence\u2010Based Review\u2014Past, Present and Future","volume":"7","author":"Dehal A.","year":"2016","journal-title":"Journal of Gastrointestinal Oncology"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-014-4147-y"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-009-0341-8"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2016.06.007"},{"key":"e_1_2_10_12_1","first-page":"99","article-title":"Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Review of Factors Contributing to Morbidity and Mortality","volume":"7","author":"Newton A. 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