{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T13:34:14Z","timestamp":1781616854588,"version":"3.54.5"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T00:00:00Z","timestamp":1732579200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>This study evaluates the prognostic value of venous tumor thrombus (VTT) in patients with advanced renal cell carcinoma (RCC) undergoing radical resection and inferior vena cava (IVC) thrombectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective review of patients with radical nephrectomy for RCC and associated VTT (2000\u22122024). Patients were dichotomized into Neves 0\u2212II (infrahepatic) and Neves III\u2212IV groups (suprahepatic) IVC involvement for univariate analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 64 patients (34 Neves 0\u2212II and 30 Neves III\u2212IV) were analyzed. No significant differences in patient or cancer characteristics. Neves III\u2212IV was associated with greater blood loss (&gt;\u20092\u2009L) (62.1% vs. 37.9%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02), greater intensive care unit length of stay (LOS) (4.4 vs. 1.4 days,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02), and postoperative LOS (11.0 vs. 6.5 days,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005). Overall, 30\u2010day mortality was only 1.6% with a mean follow\u2010up of 56.1 months. Local recurrence was 7.8% and IVC patency 96.9%. One\u2010year survival was 82.0%, 5\u2010year survival was 58.4%, and 15\u2010year survival was 42.5% without significant difference between Neves levels.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Radical nephrectomy with VTT thrombectomy and primary IVC repair is safe with high early survival and low local recurrence. Extent of IVC tumor thrombus extension is not a poor prognostic factor for early or late survival.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jso.28020","type":"journal-article","created":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T01:33:54Z","timestamp":1732671234000},"page":"917-924","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Late Survival and Long\u2010Term Follow\u2010Up After Radical Resection of Advanced Renal Cell Carcinoma With Associated Venous Tumor Thrombus"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5738-3351","authenticated-orcid":false,"given":"Calvin L.","family":"Chao","sequence":"first","affiliation":[{"name":"Department of Surgery, Division of Vascular Surgery Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nidhi K.","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Vascular Surgery Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxime","family":"Visa","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Vascular Surgery Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shilajit D.","family":"Kundu","sequence":"additional","affiliation":[{"name":"Department of Urology, Division of Urologic Oncology Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark K.","family":"Eskandari","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Vascular Surgery Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2017.9"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.14740\/wjon1279"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.04.071"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccao.2022.07.011"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.21037\/cdt.2017.09.16"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000104672.37029.4b"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2011.12.006"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11934-021-01036-y"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2017.01.001"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.25271"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2016.06.029"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1987.tb04832.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2010.11.017"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2021.08.016"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-021-08508-x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.01.039"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.05.134"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/1538574408320525"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2004.04897.x"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2012.11174.x"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2021.06.021"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsvi.2023.100048"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-017-1257-6"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12515"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCP7LKLZ8JSJQRG"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2010.10.001"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2008.07.053"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-019-5359-0"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2011.05.029"}],"container-title":["Journal 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