{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T19:39:44Z","timestamp":1754163584891,"version":"3.41.2"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T00:00:00Z","timestamp":1737417600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Stockholm, Sweden had among the highest excess mortality rates during the first wave of the SARS\u2010CoV\u20102 pandemic. In March 2020, an entire hospital implemented an infection\u2010free cold site infrastructure and scaled up imperative mainly colorectal cancer surgery, for the Stockholm health care region. The study evaluated the efficacy of the concept.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Strict preadmission screening and prophylactic interventions were implemented. The outcomes of the cold site cohort (30th March\u201321st June 2020) were compared to a prepandemic control. Population\u2010based data on colorectal cancer patients were collected from the Swedish Colorectal Cancer Registry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 107 patients in the cold site cohort and 109 in the control cohort. None developed COVID\u201019 within 30 days postoperatively. The proportions of pelvic and laparoscopic surgery were similar. The cold site cohort had more potentially avoidable stomas (32\/94 (34%) vs 19\/91 (21%), <jats:italic>p<\/jats:italic>\u2009=\u20090.0442). In the region, the proportion of colorectal cancer resections at the cold site increased from prepandemic 12.9% (58 of 448) to 43.3% (94 of 217) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A SARS\u2010CoV\u20102\u2010cold site can be kept infection\u2010free by screening, allowing increased volumes of colorectal cancer surgery with outcomes comparable to prepandemic practice. The cold site model should be more widely adopted in future similar scenarios.<\/jats:p><\/jats:sec><jats:sec><jats:title>Summary<\/jats:title><jats:p>This study reports on the implementation of an entire cold site hospital for imperative colorectal surgery, in particular colorectal cancer, during the SARS\u2010CoV\u20102 pandemic. By comparing outcomes to prepandemic practices, we demonstrated that the cold site hospital was effective in preventing infection and safely increasing surgical volume many\u2010fold.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.28094","type":"journal-article","created":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T00:39:56Z","timestamp":1737506396000},"page":"168-174","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Colorectal Cancer Surgery at a Regional Cold Site Centre During the SARS\u2010CoV\u20102 Pandemic: A Comparison With Prepandemic Practices"],"prefix":"10.1002","volume":"132","author":[{"given":"Mattias","family":"Soop","sequence":"first","affiliation":[{"name":"Department of Inflammatory Bowel Disease and Intestinal Failure Surgery Karolinska University Hospital Stockholm Sweden"},{"name":"Karolinska Institutet at Danderyd Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kajsa","family":"Anderin","sequence":"additional","affiliation":[{"name":"Department of Surgery Ersta Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik","family":"Syk","sequence":"additional","affiliation":[{"name":"Department of Surgery Ersta Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonas","family":"Nygren","sequence":"additional","affiliation":[{"name":"Karolinska Institutet at Danderyd Hospital Stockholm Sweden"},{"name":"Department of Surgery Ersta Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7738-9806","authenticated-orcid":false,"given":"Josefin","family":"Segelman","sequence":"additional","affiliation":[{"name":"Department of Surgery Ersta Hospital Stockholm Sweden"},{"name":"Department of Molecular Medicine and Surgery Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,1,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31182-X"},{"key":"e_1_2_8_3_1","article-title":"Elective Cancer Surgery in COVID\u201019\u2013Free Surgical Pathways During the SARS\u2010CoV\u20102 Pandemic: An International, Multicenter, Comparative Cohort Study","volume":"39","author":"Glasbey J. 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