{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:22:52Z","timestamp":1761128572048},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,19]],"date-time":"2006-07-19T00:00:00Z","timestamp":1153267200000},"content-version":"vor","delay-in-days":10791,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[1977,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Twenty\u2010nine histologically verified cases of Paget's disease of the breast treated at the Hadassah University Hospital in the years 1949\u20131972 were followed up and analyzed. Dividing this material into two groups according to the presence or absence of a palpable breast tumor revealed significant difference in behavior and survival. Patients with a breast mass (34%) had a 50% axillary lymph node involvement and behaved as with any other ordinary breast cancer, with a 5\u2010year survival rate of 40% and a 10\u2010year survival rate of 33%. Patients with no palpable breast mass (66%) had only a 10.5% lymph node involvement, the 5\u2010year survival rate being 94% and the 10\u2010year survival rate being 91%. Delay in diagnosis seems to play no significant factor in survival rates and outcome. We believe radical mastectomy to be the treatment of choice in all cases of Paget's disease of the breast.<\/jats:p>","DOI":"10.1002\/jso.2930090114","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T03:22:21Z","timestamp":1171941741000},"page":"93-98","source":"Crossref","is-referenced-by-count":11,"title":["Paget's disease of the breast"],"prefix":"10.1002","volume":"9","author":[{"given":"H.","family":"Freund","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Maydovnik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Laufer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. L.","family":"Durst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197009)26:3<680::AID-CNCR2820260329>3.0.CO;2-P"},{"key":"e_1_2_1_3_1","first-page":"773","article-title":"Prognosis in Paget's disease of the breast","volume":"35","author":"Colcock B. P.","year":"1954","journal-title":"Surg. Clin. N. Amer."},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1956.01270200040008"},{"key":"e_1_2_1_5_1","first-page":"317","article-title":"Preclinical Paget's disease of the nipple","volume":"93","author":"Dockerty M. B.","year":"1951","journal-title":"Surg. Gynecol. Obstet."},{"key":"e_1_2_1_6_1","unstructured":"Freund H. Peterburg I. andDurst A. L.(1975). Radical mastectomy for mammary carcinoma. Proceedings 9th European Federation Congress Internationsl College of Surgeons p.210."},{"key":"e_1_2_1_7_1","first-page":"545","volume-title":"Diseases of the breast","author":"Haagensen C. D.","year":"1965"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.18004318106"},{"key":"e_1_2_1_9_1","first-page":"1010","article-title":"Paget's disease of the nipple","volume":"123","author":"Kay S.","year":"1966","journal-title":"Surg. Gynecol. Obstet."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(70)90185-6"},{"key":"e_1_2_1_11_1","first-page":"1253","article-title":"Paget's disease in the female breast","volume":"128","author":"Maier W. P.","year":"1969","journal-title":"Surg. Gynecol. Obstet."},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000224967"},{"key":"e_1_2_1_13_1","first-page":"562","article-title":"Paget's disease of the breast","volume":"45","author":"McGregor J. K.","year":"1959","journal-title":"Surgery"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197006010-00007"},{"key":"e_1_2_1_15_1","first-page":"87","article-title":"On disease of the mammary areola preceding cancer of the mammary gland","volume":"10","author":"Paget J.","year":"1874","journal-title":"St. Barth. Hosp. Reports"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000224484"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-194207000-00003"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.2930090114","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.2930090114","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T04:58:42Z","timestamp":1699851522000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.2930090114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1977,1]]}},"alternative-id":["10.1002\/jso.2930090114"],"URL":"https:\/\/doi.org\/10.1002\/jso.2930090114","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,1]]}}}