{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T05:40:22Z","timestamp":1699854022426},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,19]],"date-time":"2006-07-19T00:00:00Z","timestamp":1153267200000},"content-version":"vor","delay-in-days":10061,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[1979,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The relative frequency of lymphocytes with surface immunoglobulins (sIgM, sIgG, sIgA) was studied in breast\u2010cancer patients' axillary lymph nodes by the immunofluorescence technique. The study encompassed a total of 105 patients, most of whom had infiltrating ductal carcinoma (IDC). The results have indicated a significantly higher ( p &lt; 0.005) average percentage of sIgM positive lymphocytes in lymph nodes in the group of IDC patients with lymph\u2010node metastasis. Shortterm followup was available for a limited number of patients, but no conclusions were reached with respect to sIgM positive lymphocytes. It is suggested that evaluation of axillary lymph\u2010node and peripheral blood lymphocyte subpopulations for each cancer patient would provide new information which could aid in determining the extent of the disease process. Moreover, such information may be of assistance in decisions of therapeutic modalities, detection of occult metastasis, and prediction of prognosis.<\/jats:p>","DOI":"10.1002\/jso.2930110114","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T04:47:24Z","timestamp":1171946844000},"page":"79-84","source":"Crossref","is-referenced-by-count":1,"title":["The relationship between slgM positive lymph\u2010node lymphocytes and breast cancer metastasis"],"prefix":"10.1002","volume":"11","author":[{"given":"Arnis","family":"Richters","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mimi","family":"Paller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"205","article-title":"The structure and metabolism of lymphocyte membranes","volume":"18","author":"Ladoulis CT","year":"1975","journal-title":"Progr Allergy"},{"key":"e_1_2_1_3_2","first-page":"1","volume-title":"Advances in Immunology","author":"Singer SJ","year":"1974"},{"key":"e_1_2_1_4_2","first-page":"67","volume-title":"Advances in Immunology","author":"Warner NL","year":"1974"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1101378"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830050812"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197501)35:1<129::AID-CNCR2820350118>3.0.CO;2-5"},{"key":"e_1_2_1_8_2","first-page":"610","article-title":"Human bredst cancer and lymph node lymphocyte surface immunoglobulins","volume":"35","author":"Richters A","year":"1974","journal-title":"Fed Proc"},{"key":"e_1_2_1_9_2","first-page":"549","article-title":"In vitro studies of axillary lymph node cells in patients with breast cancer","volume":"54","author":"Tsakraklides E","year":"1975","journal-title":"J Natl Cancer Inst"},{"key":"e_1_2_1_10_2","first-page":"80","volume-title":"Immunological Parameters of Host\u2010Tumor Relationships","author":"Black MM","year":"1973"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.2930110114","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.2930110114","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T04:58:06Z","timestamp":1699851486000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.2930110114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1979,1]]}},"alternative-id":["10.1002\/jso.2930110114"],"URL":"https:\/\/doi.org\/10.1002\/jso.2930110114","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,1]]}}}