{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:44:09Z","timestamp":1768437849798,"version":"3.49.0"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,7,19]],"date-time":"2006-07-19T00:00:00Z","timestamp":1153267200000},"content-version":"vor","delay-in-days":9514,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[1980,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Fifty\u2010one evaluable patients with liposarcomas were reviewed. Two\u2010thirds of the patients were referred after local recurrence. One\u2010third with primary surgery at RPMI had local recurrence rate of 31.6%. Overall, one or more local recurrences presented in 78% of patients. Pulmonary metastases occurred in 45%, while liver metastases in 13.6%.<\/jats:p><jats:p>Most common primary sites were the lower extremity, followed by the retroperitoneal area and upper extremity.<\/jats:p><jats:p>Median survival is better for upper and lower extremities than other areas (P &lt; 0.01). The median survival was longer in the group that received radiation after resection although the difference was not statistically significant. The high rate of local recurrences suggests the adjuvant use of radiation postoperatively when the surgical margins have not been adequate.<\/jats:p><jats:p>Sixteen patients are alive and disease\u2010free, with 10 of them having had five years or longer follow\u2010up.<\/jats:p>","DOI":"10.1002\/jso.2930140309","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T07:14:35Z","timestamp":1171955675000},"page":"245-249","source":"Crossref","is-referenced-by-count":41,"title":["Liposarcomas: Prognosis and management"],"prefix":"10.1002","volume":"14","author":[{"given":"C.","family":"Celik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. P.","family":"Karakousis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Moore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. 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A study of 105 cases","volume":"36","author":"Pach GT","year":"1954","journal-title":"Surgery"},{"key":"e_1_2_1_12_2","first-page":"62","article-title":"Prospective randomized evaluation of the role of limb\u2010Sparing surgery, radiation therapy, and adjuvant chemoimmunotherapy in the treatment of adult soft\u2010Tissue sarcomas","volume":"84","author":"Rosenberg SA","year":"1978","journal-title":"Surgery"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197508)36:2 <759::AID-CNCR2820360821>3.0.CO;2-U"},{"key":"e_1_2_1_14_2","first-page":"86","article-title":"Liposarcoma \u2013 The malignant tumor of lipoblast","volume":"119","author":"Stout AP","year":"1944","journal-title":"Ann Surg"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.2930140309","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.2930140309","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T23:24:33Z","timestamp":1699831473000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.2930140309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,7]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1980,7]]}},"alternative-id":["10.1002\/jso.2930140309"],"URL":"https:\/\/doi.org\/10.1002\/jso.2930140309","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,7]]}}}