{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T09:03:13Z","timestamp":1762160593136},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,7,20]],"date-time":"2006-07-20T00:00:00Z","timestamp":1153353600000},"content-version":"vor","delay-in-days":9423,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[1980,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Four hundred fifty\u2010three patients are evaluated regarding 10\u2010year survival rates. Females comprise 66%, and males the remainder (34%). The absolute 10\u2010year survival rate was 55.2% post therapy. Females had a remarkably better survival (64%) than the males (42%). Age did not affect the prognosis. Staging was most important in that 167 patients with Stage I had a 10\u2010year survival of 66%, which dropped for the 263 patients in Stage II (24%), and of the 23 patients classified as Stage III, only one (4%) survived 10 years. Of the 202 patients in clinical Stage I, 102 were subjected to an elective groin dissection which revealed occult metastases to lymph nodes in 35, whose 10\u2010year survival rate was 49%. In 100 patients, no elective groin dissection was performed, and 41 of these developed metastases to inguinal nodes at a later date. The 10\u2010year survival for that group was 32% \u2014 somewhat lower than the 49%. An elective groin dissection is indicated for invasive melanomas. An eleven percent mortality between the fifth and tenth year after therapy indicates that 10\u2010year survival rates should be recorded for melanomas.<\/jats:p>","DOI":"10.1002\/jso.2930150207","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T07:09:23Z","timestamp":1171955363000},"page":"147-169","source":"Crossref","is-referenced-by-count":7,"title":["Malignant melanoma of the lower extremity: Evaluation of 453 patients"],"prefix":"10.1002","volume":"15","author":[{"given":"Irving M.","family":"Ariel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(195301)6:1<1::AID-CNCR2820060102>3.0.CO;2-C"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197109)28:3<721::AID-CNCR2820280330>3.0.CO;2-1"},{"key":"e_1_2_1_4_2","first-page":"601","article-title":"Tridimensional resection of malignant melanoma","volume":"139","author":"Ariel IM","year":"1974","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_1_5_2","first-page":"135","volume-title":"Clinical Aspects of Melanotic Tumors","author":"Attie JN","year":"1964"},{"key":"e_1_2_1_6_2","first-page":"218","article-title":"A study of 650 observed malignant melanomas in the south\u2010west region","volume":"43","author":"Bodenham DC","year":"1968","journal-title":"Ann R Coll Surg Engl"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6109(16)38796-5"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197511000-00007"},{"key":"e_1_2_1_9_2","first-page":"705","article-title":"The histogenesis and biologic behavior of primary human malignant melanomas of the skin","volume":"29","author":"Clark WH","year":"1969","journal-title":"Cancer Res"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","unstructured":"(a).DasGuptaTK: Results of treatment of 269 patients with primary cutaneous melanoma: A five\u2010year prospective study.Ann Surg186\u2013201 1977.","DOI":"10.1097\/00000658-197708000-00013"},{"key":"e_1_2_1_11_2","first-page":"327","article-title":"A clinical pathologic study of prognostic factors in cutaneous malignant melanoma","volume":"144","author":"Elias EG","year":"1977","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197009)26:3<606::AID-CNCR2820260317>3.0.CO;2-M"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197401000-00020"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-195912000-00004"},{"key":"e_1_2_1_15_2","first-page":"470","volume-title":"The Lymphatics in Cancer","author":"Haagensen LD","year":"1972"},{"key":"e_1_2_1_16_2","first-page":"145","volume-title":"Melanoma: Current Problems in Surgery","author":"Knutson CO","year":"1971"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(195809\/10)11:5<1025::AID-CNCR2820110525>3.0.CO;2-3"},{"key":"e_1_2_1_18_2","first-page":"414","article-title":"The current rapid increase in mortality from malignant melanoma in developed societies","volume":"2","author":"Lee JAH","year":"1976","journal-title":"Pig Cell"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12627607"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197707)40:1<389::AID-CNCR2820400155>3.0.CO;2-I"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1971.tb50302.x"},{"key":"e_1_2_1_22_2","first-page":"427","article-title":"Amputation for melanoma of the extremity","volume":"54","author":"McPeak CJ","year":"1963","journal-title":"Surgery"},{"key":"e_1_2_1_23_2","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/S0030-5898(20)30864-6","article-title":"Hemipelvectomy in lower extremity tumors","volume":"8","author":"Miller TR","year":"1977","journal-title":"Orthop Clin North Am"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196507000-00003"},{"key":"e_1_2_1_25_2","first-page":"11","article-title":"The pigmented mole and the malignant melanoma","volume":"12","author":"Pack GT","year":"1962","journal-title":"CA"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-195212000-00001"},{"key":"e_1_2_1_27_2","first-page":"571","article-title":"Subungual meianoma","volume":"124","author":"Pack GT","year":"1967","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_1_28_2","first-page":"195","volume-title":"Progress in Clinical Cancer","author":"Shah JP","year":"1975"},{"key":"e_1_2_1_29_2","first-page":"591","article-title":"Melanomas of childhood","volume":"25","author":"Spitz S","year":"1948","journal-title":"Am J Pathol"},{"key":"e_1_2_1_30_2","unstructured":"SutherlandEM KlopferHW MansellPW KrementzET:Familial melanoma. 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