{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T14:03:37Z","timestamp":1756994617480},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,19]],"date-time":"2006-07-19T00:00:00Z","timestamp":1153267200000},"content-version":"vor","delay-in-days":9330,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[1981,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>One hundred and twenty patients with malignancy of the nasopharynx were reviewed. The most common presenting symptoms of this disease were cervical mass and hearing loss. Neoplasm occurred three times more frequently in males than in females. Cranial nerve dysfunction was present in 17.5% of patients at the time of initial evaluation.<\/jats:p><jats:p>The overall 3\u2010 and 5\u2010year determinate survival for the entire series of nasopharyngeal malignancies was 38.9, and 27.0%, respectively. Nonsquamous cell malignancies demonstrated a better 5\u2010year survival (42%) than squamous cell and undifferentiated neoplasms (24%).<\/jats:p><jats:p>The presence of cervical metastases offered a poorer prognosis. A 39.6% 5\u2010year survival was recorded for patients without nodal disease. Massive lymphadenopathy or bilateral cervical metastases forecasted an ominous 5\u2010year survival of 13.6%.<\/jats:p><jats:p>Control rate was greatest among patients with tumors restricted to one area of the nasopharynx and without regional metastases. The 5\u2010year survival of such patients was 71.4% compared to 13.3% for patients having tumor extension beyond the nasopharynx producing cranial nerve impairment or bone erosion.<\/jats:p>","DOI":"10.1002\/jso.2930170105","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T07:59:03Z","timestamp":1171958343000},"page":"25-32","source":"Crossref","is-referenced-by-count":7,"title":["Malignant tumors of the nasopharynx"],"prefix":"10.1002","volume":"17","author":[{"given":"Shan Ray","family":"Baker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"18","volume-title":"Cancer of the Nasopharynx","author":"Bailar JC","year":"1967"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196907)24:1<1::AID-CNCR2820240102>3.0.CO;2-H"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1148\/99.1.165"},{"key":"e_1_2_1_5_2","first-page":"35","article-title":"Nasopharyngeal tumors: Three to five year survivals","volume":"89","author":"Hare HF","year":"1963","journal-title":"Am J Roentgenol"},{"key":"e_1_2_1_6_2","first-page":"1196","article-title":"Nasopharyngeal carcinoma: Recent studies and outlook for a viral etiology","volume":"34","author":"de\u2010The G","year":"1974","journal-title":"Cancer Res"},{"key":"e_1_2_1_7_2","first-page":"1207","article-title":"Antibodies to herpes group viruses in patients with nasopharyngeal and other head and neck cancers","volume":"34","author":"Henderson BE","year":"1974","journal-title":"Cancer Res"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.1977.87.11.1932"},{"key":"e_1_2_1_9_2","doi-asserted-by":"crossref","unstructured":"BakerSR: Nasopharyngeal carcinoma: Clinical course and results of therapy.Head Neck Surg(in press)1980.","DOI":"10.1002\/hed.2890030104"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197606)37:6<2787::AID-CNCR2820370633>3.0.CO;2-O"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(78)90138-4"},{"key":"e_1_2_1_12_2","unstructured":"Manual for staging of cancer. 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