{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T00:28:12Z","timestamp":1699835292918},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,7,19]],"date-time":"2006-07-19T00:00:00Z","timestamp":1153267200000},"content-version":"vor","delay-in-days":8814,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[1982,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A general review of reports on the chromosomal effects of oral contraceptive has been undertaken, and it is quite apparent that there is a scarcity of literature on these very important investigations. Also, those that have been undertaken, cannot be properly assessed on account of, one supposes, subjects' background and lack of numbers, differences in techniques and, above all, the small number of metaphases analyzed.<\/jats:p><jats:p>Apart from the report by Mills and colleagues [16], none of the reports mentioned exogenous agents to which the subjects might have been exposed, especially in cases where there has been an increased frequency of chromosomal aberrations. All these considerations must be taken into account for, as yet, the reports are too conflicting to \u201aindict\u2019\ufe01 the oral contraceptive as having chromosome\u2010breaking properties.<\/jats:p>","DOI":"10.1002\/jso.2930200210","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T08:23:24Z","timestamp":1171959804000},"page":"115-118","source":"Crossref","is-referenced-by-count":0,"title":["The chromosomal effects of the oral contraceptive"],"prefix":"10.1002","volume":"20","author":[{"given":"Nutan P.","family":"Bishun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1508\/cytologia.37.639"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0027-5107(75)90205-5"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(67)92262-3"},{"key":"e_1_2_1_5_2","first-page":"343","article-title":"Chromosome studies in selected spontaneous abortions. 1. 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Papers 14\u201319 1969."},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1968.tb11956.x"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016347509157773"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(75)90921-7"},{"key":"e_1_2_1_14_2","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1016\/S0015-0282(16)41299-9","article-title":"Comparison of chromosome breakages in lymphocytes and fibroblasts from control women and women taking oral contraceptives","volume":"26","author":"Littlefield LG","year":"1975","journal-title":"Fert Steril"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0010-7824(74)90129-2"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(70)90249-8"},{"key":"e_1_2_1_17_2","first-page":"141","article-title":"Chromosomes and oral contraceptives: aberrations in relation to neoplasia","volume":"1","author":"Mills JN","year":"1975","journal-title":"Clin Oncol"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1218(79)90142-3"},{"key":"e_1_2_1_19_2","first-page":"78","volume-title":"Proc Symp 19\u2010Nor\u2010Progestational Steroids","author":"Rice\u2010Wray E","year":"1957"},{"key":"e_1_2_1_20_2","first-page":"190","article-title":"Oral contraceptives and in vivo cytogenetic studies","volume":"39","author":"Shapiro LR","year":"1972","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420040114"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0190581"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.3.3.186"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.2930200210","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.2930200210","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T23:44:11Z","timestamp":1699832651000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.2930200210"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,6]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1982,6]]}},"alternative-id":["10.1002\/jso.2930200210"],"URL":"https:\/\/doi.org\/10.1002\/jso.2930200210","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,6]]}}}