{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:20:40Z","timestamp":1760188840217},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,7,19]],"date-time":"2006-07-19T00:00:00Z","timestamp":1153267200000},"content-version":"vor","delay-in-days":8449,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[1983,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Twenty\u2010six patients with adenocarcinomas of the rectum, rectosigmoid, or sigmoid colon given adjuvant pre\u2010 or postoperative pelvic radiation therapy followed at least 5 years were retrospectively reviewed to evaluate late tumor control and complication rates. The overall 7\u2010year survival rate was 80 \u00b1 8% with B<jats:sub>2,3<\/jats:sub>, patients faring better than C<jats:sub>2,3<\/jats:sub> (94 \u00b1 6% versus 43 \u00b1 19%, p &lt; 0.005). Local pelvic tumor control was achieved in 23\/26 patients (88%); patients with high\u2010stage (C<jats:sub>2,3<\/jats:sub>) or poorly\u2010differentiated adenocarcinomas had a higher postirradiation pelvic relapse rate (3\/11) versus low stage, well or moderately\u2010well differentiated tumors (0\/15). A major complication (none fatal) occurred in 2 of 26 patients (8%) and was not correlated with either irradiation dose nor volume.<\/jats:p><jats:p>Long\u2010term follow\u2010up is now available on patients who received adjuvant pelvic irradiation for rectal or sigmoid carcinomas and indicates a high pelvic tumor control rate. The 8% major complication rate may be decreased in the future by more sophisticated irradiation treatment planning.<\/jats:p>","DOI":"10.1002\/jso.2930230210","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T08:46:50Z","timestamp":1171961210000},"page":"99-103","source":"Crossref","is-referenced-by-count":5,"title":["Long\u2010term survivors after adjuvant pelvic irradiation in rectal and sigmoid carcinoma: An assessment of late results"],"prefix":"10.1002","volume":"23","author":[{"given":"Gene","family":"Kopelson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"335","article-title":"Preoperative irradiation in operable cancer of the rectum: Report of the Toronto trial","volume":"20","author":"Rider WD","year":"1977","journal-title":"Can J Surg"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6109(16)42586-7"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197508)36:2 <691::AID-CNCR2820360812>3.0.CO;2-E"},{"key":"e_1_2_1_5_2","unstructured":"KopelsonG: Adjuvant postoperative radiation therapy for colorectal carcinoma above the peritoneal reflection: 1.Sigmoid colon. 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