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Measurement of chemiluminescent intensity of adherent cells obtained from mesenteric lymph nodes of treated hosts revealed elevated activities of these cells. In the clinical trials it was found that marked histiocytosis occurred in mesenteric lymph nodes of stomach and colorectal cancer patients treated by the oral BCG. The 2\u2010year survival rate of treated patients with stage IV stomach cancer (44.4%) was significantly higher than that of the untreated patients (6.3%). The results of the present study indicate that the oral BCG administration would be an effective local adjuvant therapy following radical surgery to treat patients with gastrointestinal cancer.<\/jats:p>","DOI":"10.1002\/jso.2930260206","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T09:02:58Z","timestamp":1171962178000},"page":"100-106","source":"Crossref","is-referenced-by-count":7,"title":["Oral administration of BCG as a local immunotherapy of gastrointestinal cancer"],"prefix":"10.1002","volume":"26","author":[{"given":"Masazumi","family":"Eriguchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genshichiro","family":"Fujii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"1","article-title":"Introductory remarks, in \u201cConference on the use of BCG in therapy of Cancer.\u201d","volume":"39","author":"Rapp HJ","year":"1973","journal-title":"Natl Cancer Inst Monogr"},{"key":"e_1_2_1_3_2","first-page":"229","article-title":"Immunologic approaches to various types of cancer with the use of BCG and purified protein derivatives","volume":"39","author":"Klein E","year":"1973","journal-title":"Natl Cancer Inst Monogr"},{"key":"e_1_2_1_4_2","first-page":"165","volume-title":"BCG Vaccine: Tuberculosis\u2010Cancer. 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