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The median survival from histologic diagnosis was for grade I tumors 54 months, for grade II tumors 26 months, for grade III tumors 1 month. The difference in survival between patients with grade I or II tumors and those with grade III tumors was significant (P &lt; 0.001). The majority of the patients with grade III tumors were admitted with clinical evidence of disseminated disease and died within 1 month. Among the patients with well\u2010differentiated tumors, five who received surgical treatment of their recurrence had a median survival of 51 months, whereas seven patients who received no surgical treatment had median survival of 20 months following first recurrence (0.05 &lt; P &lt; 0.10).<\/jats:p>","DOI":"10.1002\/jso.2930290208","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T10:35:35Z","timestamp":1171967735000},"page":"105-111","source":"Crossref","is-referenced-by-count":25,"title":["Adrenal adenocarcinomas: Histologic grading and survival"],"prefix":"10.1002","volume":"29","author":[{"given":"C. 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