{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T05:40:30Z","timestamp":1697953230500},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,7,19]],"date-time":"2006-07-19T00:00:00Z","timestamp":1153267200000},"content-version":"vor","delay-in-days":7718,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[1985,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>For some small rectal cancers electrofulguration can be an attractive alternative to more extensive surgical procedures. This report is a review of 49 patients who, after careful selection, were considered ideal candidates for curative fulguration in the period 1959\u20131982. All had rectal adenocarcinomas and were clinically staged as Dukes' A tumors. To put the results of this analysis into perspective, they are compared to the results of those patients (34) who also had early clinical stage rectal adenocarcinomas, but for a variety of reasons underwent abdominoperineal excisions (APE, 11 patients) or low\u2010anterior resections (LAR, 23 patients) instead of fulguration. Postoperative complications after fulguration were minimal, there were no postoperative deaths, and all patients retained anal continence. After APE or LAR there were two postoperative deaths (one myocardial infarction, one ruptured iliac aneurysm); postoperative morbidity was greater. All LAR\u2010treated patients remained continent. Of the patients at risk 55% remained disease\u2010free after fulguration, while 77% remained disease\u2010free after APE or LAR (P = 0.023). This is due to a higher percentage of loco\u2010regional recurrences occurring after fulguration than after APE or LAR (31% vs 9%, respectively, P = 0.021). The percentage of patients with distant metastases in both groups are similar. It seems that electrofulguration of rectal cancers, even in strictly selected patients in a specialized institution, can lead to an unacceptably high percentage of patients with loco\u2010regional recurrences. Nearly all local failures occurred in patients with tumors that measured more than 3 cm in diameter and\/or occupied more than one\u2010third of the rectal circumference. Salvage operations for loco\u2010regional failure were performed in 13 patients, 5 of whom are alive with no evidence of disease. Since there seems to be a direct relation between tumor size and the chance of loco\u2010regional recurrence and since salvage operations for local failure are not uniformly successful, electrofulguration for cure must be reserved for the very rare patient with a very small early\u2010stage rectal cancer.<\/jats:p>","DOI":"10.1002\/jso.2930290211","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T10:35:35Z","timestamp":1171967735000},"page":"123-128","source":"Crossref","is-referenced-by-count":4,"title":["Early\u2010stage rectal cancer: Electrofulguration in comparison to abdominoperineal extirpation or low\u2010anterior resection"],"prefix":"10.1002","volume":"29","author":[{"given":"Peter W.","family":"De Graaf","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan G.","family":"Roussel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ernst","family":"Gortzak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guus A. M.","family":"Hart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ans","family":"Jongman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emil A.","family":"Van Slooten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"391","article-title":"The role of electrocoagulation in the treatment of carcinoma of the rectum","volume":"135","author":"Crile G","year":"1972","journal-title":"SGO"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(82)90142-8"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800176810"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02553103"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1958.10501452"},{"key":"e_1_2_1_7_2","article-title":"Place of electrocoagulation in cancer of the rectum treatment. 1st congress of the European Society of Surgical Oncology. November 26\u201327, 1982, Athens, Greece","volume":"266","author":"Lasser P","year":"1982","journal-title":"European Society of Surgical Oncology"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196709000-00009"},{"key":"e_1_2_1_9_2","first-page":"164","article-title":"Electrocoagulation as a primary curative method in the treatment of carcinoma of the rectum","volume":"157","author":"Madden JL","year":"1983","journal-title":"SGO"},{"key":"e_1_2_1_10_2","first-page":"163","article-title":"Evaluation of survival data and two new rank order statistics arising in its consideration","volume":"50","author":"Mantel N","year":"1966","journal-title":"Cancer Chemoth Rep"},{"key":"e_1_2_1_11_2","unstructured":"Uche EEO: Thesis1980 Criteria for selection of patients for treatment of rectal cancer. Amsterdam."},{"key":"e_1_2_1_12_2","first-page":"174","article-title":"Failures of electrocoagulation of primary carcinoma of the rectum","volume":"138","author":"Wanebo HJ","year":"1974","journal-title":"SGO"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.2930290211","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.2930290211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T21:20:41Z","timestamp":1697923241000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.2930290211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,6]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1985,6]]}},"alternative-id":["10.1002\/jso.2930290211"],"URL":"https:\/\/doi.org\/10.1002\/jso.2930290211","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,6]]}}}