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Four cases of mild dysplasia, nine cases of moderate to severe dysplasia, two cases of carcinoma in situ and one case of invasive carcinoma were associated with condylomatous lesions. Intranuclear dark\u2010brown precipitates were observed in superficial and intermediate zones of the dysplastic epithelium. Positive reaction was seen in condylomatous epithelium associated with neoplasia. No nuclear precipitates were observed in carcinoma cells, but one noncondylomatous lesion with moderate dysplasia showed positive intranuclear staining. These preliminary findings suggest that papilloma viruses may play a role in the development of human cervical neoplasias.<\/jats:p>","DOI":"10.1002\/jso.2930320108","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T10:58:41Z","timestamp":1171969121000},"page":"25-29","source":"Crossref","is-referenced-by-count":0,"title":["The demonstration of papilloma virus in cervical dysplasia and\/or neoplasia"],"prefix":"10.1002","volume":"32","author":[{"given":"Luna","family":"Ghosh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Venkat R.","family":"Nadimpalli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salve G.","family":"Ronan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Abel L.","family":"Robertson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"issue":"5","key":"e_1_2_1_2_2","first-page":"617","article-title":"Human papillomavirus lessions in association with cervical dysplasias and neoplasias","volume":"62","author":"Syrjanen KJ","year":"1983","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02110679"},{"key":"e_1_2_1_4_2","first-page":"53","article-title":"Electron microscopic detection of papilloma virus particles in selected koilocytotic cells in a routine cervical smear","volume":"23","author":"Hills EL","year":"1979","journal-title":"Acta Cytol"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(83)90080-X"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(16)31169-5"},{"issue":"5","key":"e_1_2_1_7_2","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/S0025-7125(16)31166-X","article-title":"Genital infections","volume":"67","author":"de la Maza LM","year":"1983","journal-title":"Med Clin North Am"},{"key":"e_1_2_1_8_2","first-page":"1353","article-title":"A comparison review of key epidemiological studies in cervical cancer related to current searches for transmissible agents","volume":"33","author":"Rotkin ID","year":"1973","journal-title":"Cancer Res."},{"key":"e_1_2_1_9_2","first-page":"783","article-title":"Human cervical cancer as a venereal disease","volume":"36","author":"Kessler II","year":"1976","journal-title":"Cancer Res."},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)90006-5"},{"key":"e_1_2_1_11_2","first-page":"495","article-title":"Immunologic Relatedness of papillomaviruses from different species","volume":"64","author":"Jenson AB","year":"1980","journal-title":"JNCI"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198301000-00004"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(81)90087-9"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.2.560"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.79.14.4437"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.2930320108","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.2930320108","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T09:43:36Z","timestamp":1697881416000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.2930320108"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,5]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1986,5]]}},"alternative-id":["10.1002\/jso.2930320108"],"URL":"https:\/\/doi.org\/10.1002\/jso.2930320108","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,5]]}}}