{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T12:12:41Z","timestamp":1697976761306},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,7,19]],"date-time":"2006-07-19T00:00:00Z","timestamp":1153267200000},"content-version":"vor","delay-in-days":7200,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[1986,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A method is presented of rapid, palliative radiotherapy for carcinoma of the breast, composed of two sessions of 6.5 or 8.5 Gy delivered at a 48\u2010hour interval. The radiobiological equivalence of this unconventional technique is presented. Our preliminary results in a series of 80 patients were published in 1978. The present report is based on the analysis of 112 patients with T<jats:sub>4<\/jats:sub> of the breast submitted to the \u201cflash\u201d dose, from March 1978 to December 1981. The method was used not only for relief of symptoms such as pain and hemorrhage, but also as part of intensive radiotherapy in all patients with good response and with no manifestation of distant dissemination so that they were able to resume treatment 2.5 or 3 weeks later, with conventional fractionation. Some of these patients became operable. About half of the cases had castration and\/or hormone. therapy and\/or chemotherapy. In the group of patients with T<jats:sub>4<\/jats:sub>M<jats:sub>0<\/jats:sub>, 59.8% were alive after more than 1 year, and of them, 43.7% had no evidence of disease. These encouraging results suggest that this method be advocated in T<jats:sub>4<\/jats:sub> of the breast because of its rapidity and good tolerance with no significant complications.<\/jats:p>","DOI":"10.1002\/jso.2930330311","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T10:43:59Z","timestamp":1171968239000},"page":"198-202","source":"Crossref","is-referenced-by-count":0,"title":["Palliative telecobalt\u201460 with concentrated dose in TNM classification T<sub>4<\/sub> of the breast"],"prefix":"10.1002","volume":"33","author":[{"given":"M. B.","family":"Patricio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. F.","family":"Brites","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. F.","family":"Guimaraes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. B.","family":"De Jesus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. I.","family":"Catita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Vilhena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"50","article-title":"Massive single dose, weekly fractionation technique in the treatment of head and neck cancer: Preliminary report","volume":"91","author":"Atkins HL","year":"1964","journal-title":"Am J Roentgenol"},{"key":"e_1_2_1_3_2","first-page":"479","article-title":"The rapid palliative treatment of breast carcinoma","volume":"81","author":"Cochran DQ","year":"1959","journal-title":"Am J Roentgenol"},{"key":"e_1_2_1_4_2","first-page":"9","article-title":"Concentrated palliative radiotherapy for tumors affecting the oesophagus, brain and mediastinum","volume":"3","author":"Dutreix J","year":"1971","journal-title":"Ann Clin Res"},{"key":"e_1_2_1_5_2","first-page":"585","article-title":"Rapid radiotherapy for inoperable carcinoma of the breast. Benefits and complications","volume":"93","author":"Edelman AH","year":"1965","journal-title":"Am J Roentgenol"},{"key":"e_1_2_1_6_2","first-page":"838","article-title":"Resultats de l'irradiation concentr\u00e9e \u00e9 vis\u00e9e curative dans les epitheliomes cutan\u00e9s et les tumeurs vesicales","volume":"57","author":"Floiras JI","year":"1976","journal-title":"J Radiol Electrol"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.126.2.268"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1148\/78.3.439"},{"key":"e_1_2_1_9_2","first-page":"3803","article-title":"Radiotherapie pre\u2010operatoire concentr\u00e9e","volume":"82","author":"Olivier JP","year":"1975","journal-title":"Gaz Med Fr"},{"key":"e_1_2_1_10_2","first-page":"831","article-title":"Resultats de l'irradiation concentr\u00e9e dans les glioblastomes, les astrocytomes malins et les metastases c\u00e9rebrales de l'adulte","volume":"57","author":"Schlienger M","year":"1976","journal-title":"J Radiol Electrol"},{"key":"e_1_2_1_11_2","first-page":"542","article-title":"Radioterapia anti\u00e1lgica do cancro avancado","volume":"106","author":"Patricio MB","year":"1983","journal-title":"O M\u00e9dico"},{"key":"e_1_2_1_12_2","unstructured":"PatricioMB TavaresMA Guimar\u00e3esMF:The concentrated dose with 25 Mev. photon bean in the cervix carcinoma as haemostatic and anti algic purposes. (Submitted.)"},{"key":"e_1_2_1_13_2","first-page":"56","article-title":"Tratamento paliativo com irradiate\u00e3o concentrada no cancro da mama localmente avaneado","volume":"3","author":"Sim\u00f5es MJ","journal-title":"Boletim da Soc Port de Ginec"},{"key":"e_1_2_1_14_2","doi-asserted-by":"crossref","unstructured":"MikuriyaS:Relationship between radiotherapy and cellular infiltration into the tumor nests Abstracts of 4th AOCR PA.368\u2013369 Nov. 13\u201018 Bangkok 1983.","DOI":"10.1111\/j.2150-1092.1983.tb01394.x"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.2930330311","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.2930330311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T16:04:13Z","timestamp":1697904253000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.2930330311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,11]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1986,11]]}},"alternative-id":["10.1002\/jso.2930330311"],"URL":"https:\/\/doi.org\/10.1002\/jso.2930330311","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,11]]}}}