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Both patients were treated with very large doses of vitamin D<jats:sub>2<\/jats:sub> and phosphate without improvement in the osteomalacia or normalization of the serum phosphate. Complete removal of a low\u2010grade fibrosarcoma in the second patient and removal of an ossifying fibroma in the first patient resulted in a cure in both patients despite no further therapy with vitamin D or phosphate. The excessive aminoaciduria and glucosuria of the first patient also remitted. During a 14\u2010year follow\u2010up period, there has been no evidence of tumor recurrence, hypophosphatemia, or osteomalacia in either patient. The levels of 1,25\u2010dihydroxycholecalciferol remain within the normal range in both patients.<\/jats:p>","DOI":"10.1002\/jso.2930360310","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T11:12:35Z","timestamp":1171969955000},"page":"198-205","source":"Crossref","is-referenced-by-count":13,"title":["Tumor\u2010induced osteomalacia: Long\u2010term follow\u2010up of two patients cured by removal of their tumors"],"prefix":"10.1002","volume":"36","author":[{"given":"Mario","family":"Sparagana","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI108855"},{"key":"e_1_2_1_3_2","first-page":"33","article-title":"Osteomalacia with Looser's nodes (Milkman's syndrome) due to a raised resistance to vitamin D acquired about the age of 15 years","volume":"16","author":"McCance 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