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Consequently, every breast biopsy merits highly specific histopathological characterization as well as assay for hormone receptors. Certain aspects of a woman's personal and family history may be associated with increased or decreased risk. Clinical application of these variables to the prediction of future outcome requires an understanding of the definitions of risk. These definitions must then be applied appropriately when assessing risk. The definition of risk used must be explicitly stated and consistently used.<\/jats:p><jats:p>Provided is a review of the definitions of risk and the risk of acquiring breast cancer according to age, family history, and histopathological characteristics of benign breast biopsies. The highly variable relative risk of dying from breast cancer when diagnosed is also reviewed.<\/jats:p>","DOI":"10.1002\/jso.2930410113","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T11:40:08Z","timestamp":1171971608000},"page":"42-46","source":"Crossref","is-referenced-by-count":7,"title":["Breast cancer risk: A review of definitions and assessments of risk"],"prefix":"10.1002","volume":"41","author":[{"given":"John S.","family":"Spratt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard A.","family":"Greenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James G.","family":"Kuhns","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth A.","family":"Amin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_2_2","volume-title":"Primer of Epidemiology","author":"Friedman GD","year":"1979"},{"key":"e_1_2_1_3_2","volume-title":"A Dictionary of Epidemiology","author":"Last JM","year":"1983"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19850315)55:6<1372::AID-CNCR2820550635>3.0.CO;2-5"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197605)37:5<2486::AID-CNCR2820370542>3.0.CO;2-8"},{"key":"e_1_2_1_6_2","doi-asserted-by":"crossref","unstructured":"CarlileT KopeckyKJ ThompsonDJ WhiteheadJR Gilbert FIJr PresentAJ ThreattBA KrookP HadawayE:Breast cancer prediction and the Wolfe classification of mammograms. 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