{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:38:16Z","timestamp":1760981896835},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,7,20]],"date-time":"2006-07-20T00:00:00Z","timestamp":1153353600000},"content-version":"vor","delay-in-days":5771,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[1990,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We present here our findings on patients with an elevated lesion of the duodenal bulb. All these patients were treated in our clinics between the years 1984 and 1988. These lesions were present in 36 of 8,802 patients who underwent upper gastrointestinal pan\u2010endoscopy. Two patients had a duodenal carcinoma, 2 an adenoma, and 1 a Brunner's gland adenoma. There were 15 with a hyperplastic polyp, 3 with a heterogenic gastric mucosa, 3 with Brunner's gland hyperplasia, 6 with duodenitis, and 4 with regenerative mucosa. Among these 36 lesions, only 69% (25 lesions) were evident on the upper gastrointestinal X\u2010ray series. Adenoma and Brunner's gland adenoma were of a pedunculated form of the gross type and had an irregular surface mucosa. Both duodenal carcinomas were detected by endoscopic biopsy and were resected. Histologically, these lesions were limited to the submucosal layer and were of the non\u2010pedunculated polypoid form, but there were no other characteristic endoscopic features, in comparison with other elevated lesions. Thus, upper gastrointestinal endoscopy with routine observations of the duodenal bulb plus endoscopic biopsy will lead to a definite diagnosis of these elevated lesions and to the early detection and treatment of this rare malignant lesion.<\/jats:p>","DOI":"10.1002\/jso.2930450205","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T11:56:39Z","timestamp":1171972599000},"page":"79-84","source":"Crossref","is-referenced-by-count":17,"title":["Clinicopathological features of elevated lesions of the duodenal bulb"],"prefix":"10.1002","volume":"45","author":[{"given":"Hiroshi","family":"Matsuura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Kuwano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Kanematsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keizo","family":"Sugimachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukiaki","family":"Haraguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197704)39:4<1721::AID-CNCR2820390450>3.0.CO;2-M"},{"key":"e_1_2_1_3_2","first-page":"174","article-title":"Primary adenocarcinoma of the duodenum","volume":"53","author":"Gonzalez GD","year":"1987","journal-title":"Am Surg"},{"key":"e_1_2_1_4_2","first-page":"973","article-title":"Primary early carcinoma of duodenal bulb. Report of a case and review of literature (Japanese and English abstract)","volume":"18","author":"Tanigawa T","year":"1983","journal-title":"Stomach Intest"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(84)90036-9"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198001000-00003"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19880115)61:2<316::AID-CNCR2820610222>3.0.CO;2-O"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810801)48:3<799::AID-CNCR2820480324>3.0.CO;2-Q"},{"key":"e_1_2_1_9_2","first-page":"371","article-title":"Hyperplasia of Brunner's glands of duodenum","volume":"126","author":"Kaplan EL","year":"1968","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198803000-00002"},{"key":"e_1_2_1_11_2","first-page":"247","article-title":"Adenomas of the intestine","volume":"75","author":"Johansen A","year":"1969","journal-title":"Acta Pathol Microbiol Scand"},{"key":"e_1_2_1_12_2","first-page":"6","article-title":"Histological studies on duodenitis\u2014with special reference to endoscopic findings (in Japanese)","volume":"85","author":"Takamasu M","year":"1988","journal-title":"Jpn J Gastroenterol"},{"key":"e_1_2_1_13_2","first-page":"3078","article-title":"Clinicopathological investigation of heterotopic gastric mucosa in the duodenum (in Japanese)","volume":"28","author":"Uraoka M","year":"1986","journal-title":"Gastroenterol Endosc"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19840101)53:1<162::AID-CNCR2820530128>3.0.CO;2-Q"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/jso.2930330305"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.2930450205","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.2930450205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T01:31:09Z","timestamp":1698024669000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.2930450205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,10]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1990,10]]}},"alternative-id":["10.1002\/jso.2930450205"],"URL":"https:\/\/doi.org\/10.1002\/jso.2930450205","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,10]]}}}