{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T23:55:18Z","timestamp":1793836518204,"version":"4.6.1"},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,7,19]],"date-time":"2006-07-19T00:00:00Z","timestamp":1153267200000},"content-version":"vor","delay-in-days":5619,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[1991,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Obstructive jaundice developed in a patient concomitantly with the diagnosis of breast carcinoma. Abdominal exploration disclosed a metastatic tumor in the head of the pancreas, the distal bile duct, and the gallbladder. A cholecystectomy and choledochojejunostomy were performed and later, because of intestinal obstruction, the patient underwent gastrojejunostomy. Pathological examination demonstrated metastatic lobular carcinoma of breast with strongly positive staining for estradiol. Additional hormonal therapy has been given to the patient since the operation. The patient is alive 16 months after the diagnosis of her disease.<\/jats:p><jats:p>This case suggests that a vigorous diagnostic approach should be adopted in every jaundiced patient with metastatic breast cancer in order to exclude causes of jaundice other than diffuse metastatic involvement of the liver. Patients with extrahepatic biliary metastasis should be treated by aggressive surgical treatment, combined with systemic therapy which can offer them significant palliation and better survival.<\/jats:p>","DOI":"10.1002\/jso.2930460318","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T11:53:13Z","timestamp":1171972393000},"page":"211-214","source":"Crossref","is-referenced-by-count":45,"title":["Biliary and pancreatic metastases of breast carcinoma: Is surgical palliation indicated?"],"prefix":"10.1002","volume":"46","author":[{"given":"Itzhak","family":"Pappo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elad","family":"Feigin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Uziely","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gail","family":"Amir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_2_2","volume-title":"Diseases of the Breast","author":"Haagensen CD","year":"1986"},{"key":"e_1_2_1_3_2","first-page":"1","article-title":"Factors influencing survival in patients with untreated hepatic metastases","volume":"127","author":"Jaffe BM","year":"1968","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(80)90203-6"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19870701)60:1<96::AID-CNCR2820600117>3.0.CO;2-S"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(80)90066-8"},{"key":"e_1_2_1_7_2","first-page":"113","article-title":"Diagnosis and treatment of obstructive jaundice secondary to liver metastases","volume":"41","author":"Meyer JE","year":"1917","journal-title":"Cancer"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-91-4-568"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1968.01330230148023"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1159\/000171912"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/jso.2930110303"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196403000-00026"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02239526"},{"key":"e_1_2_1_14_2","volume-title":"Diagnostic Histopathlogy of the Breast","author":"Page DL","year":"1988"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19811015)48:8<1830::AID-CNCR2820480821>3.0.CO;2-H"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.156.3.4023221"},{"key":"e_1_2_1_17_2","first-page":"1197","volume-title":"Cancer: Principles and Practice in Oncology","author":"Henderson IC","year":"1989"},{"key":"e_1_2_1_18_2","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1097\/00003086-198404000-00016","article-title":"Carcinoma of the breast metastatic to the skeleton","volume":"184","author":"Miller F","year":"1984","journal-title":"Clin Orthop"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.2930460318","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.2930460318","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T02:27:26Z","timestamp":1698028046000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.2930460318"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,3]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1991,3]]}},"alternative-id":["10.1002\/jso.2930460318"],"URL":"https:\/\/doi.org\/10.1002\/jso.2930460318","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,3]]}}}