{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T08:10:45Z","timestamp":1698307845335},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,7,19]],"date-time":"2006-07-19T00:00:00Z","timestamp":1153267200000},"content-version":"vor","delay-in-days":4674,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[1993,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The pharmacokinetics of cisplatin instilled into the pleural cavity in patients with malignant pleurisy due to lung cancer were studied. Higher concentrations of total and free platinum in pleural effusion have been maintained for longer than 72 hours in patients who were subjected to panpleuropneumonectomy than in those who received simple drainage. Early rapid drop of total platinum within 6 hours was significant in the drainage group. Total platinum level in the serum of the panpleuropneumonectomy group gradually increased during 1\u201372 hours, however, that of the drainage group was highest at 1 hour after instillation and declined gradually with time. Free platinum in the serum was also present at lower concentrations in the panpleuropneumonectomy group than in the drainage group. These facts may be ascribed to the absorptive activity of parietal pleura which is present in the drainage group but absent in the panpleuropneumonectomy group. In summary, removal of the parietal pleura by panpleuropneumonectomy could cause cisplatin to be not only more active but also less toxic in patients with malignant pleurisy due to lung cancer. \u00a9 1993 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jso.2930540202","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T13:18:50Z","timestamp":1171977530000},"page":"67-70","source":"Crossref","is-referenced-by-count":8,"title":["Pharmacokinetics of cisplatin instilled into the pleural cavity following panpleuropneumonectomy in patients with malignant pleurisy due to lung cancer"],"prefix":"10.1002","volume":"54","author":[{"given":"Kosei","family":"Yasumoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiro","family":"Shimokawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Nagashima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuyuki","family":"Hirose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisashi","family":"Nakahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"24","article-title":"Management of malignant pleural effusion: An overview","volume":"15","author":"Ruckdeschel JC","year":"1988","journal-title":"Semin Oncol"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197503)35:3<734::AID-CNCR2820350328>3.0.CO;2-N"},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1016\/S0022-5223(19)36678-4","article-title":"Neoadjuvant chemotherapy and operations in the treatment of lung cancer with pleural effusion","volume":"101","author":"Reyes L","year":"1991","journal-title":"J Thorac Cardiovasc Surg"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-76784-5_5"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950130406"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1991.9.2.313"},{"key":"e_1_2_1_8_2","first-page":"285","volume-title":"Cisplatin, Current Status and New Development","author":"Repta AJ","year":"1980"},{"key":"e_1_2_1_9_2","first-page":"68","article-title":"Antitumor activity and toxicity of serum protein\u2010bound platinum formed from cisplatin","volume":"76","author":"Takahashi K","year":"1985","journal-title":"Jpn J Cancer Res"},{"key":"e_1_2_1_10_2","first-page":"885","volume-title":"The Lung, Scientific Foundations","author":"Miserocchi G","year":"1991"},{"key":"e_1_2_1_11_2","volume-title":"TNM Classification of Malignant Tumors","author":"Hermanek P","year":"1987"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1552-4604.1988.tb03134.x"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00047607"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0169-5002(91)90005-Q"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.2930540202","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.2930540202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T14:14:22Z","timestamp":1698243262000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.2930540202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,10]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1993,10]]}},"alternative-id":["10.1002\/jso.2930540202"],"URL":"https:\/\/doi.org\/10.1002\/jso.2930540202","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,10]]}}}