{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T08:12:17Z","timestamp":1698394337228},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,19]],"date-time":"2006-07-19T00:00:00Z","timestamp":1153267200000},"content-version":"vor","delay-in-days":4217,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[1995,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A retrospective study was conducted of 993 malignant tumors of the lung in 977 patients. The male\u2010female sex ratio was 2.6:1. The age distribution of the males did not differ from that of the females and the overall mean age was 64.3 \u00b1 9.5 years (range, 13\u201385 years). Forty\u2010three percent of the patients were in their seventh decade. The location was peripheral in 81% of the tumors and central in 19%. Of the central tumors, 85% were squamous cell (epidermoid) carcinoma (SCC), while 58% of the peripheral tumors were adenocarcinoma (ADENO). In males, 49% of all tumors were SCC and 36% ADENO, while in females 76% were ADENO. The incidence of positive lymph node metastasis increased in parallel with the pT status in both central and peripheral carcinomas. However, it was noted that, of peripheral lung carcinomas, no SCC with a diameter of 15 mm or less had lymph node metastasis, whereas 18.9% of the ADENO of this size were positive for lymph node metastasis. These results indicate that lymph node metastasis can occur even in small\u2010sized peripheral ADENO less than 15 mm. Thus, early detection and surgery together with mediastinal lymph node dissection are necessary even for small\u2010sized tumors to improve the prognosis in patients with peripheral ADENO of the lung. \u00a9 1995 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jso.2930580103","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T13:38:44Z","timestamp":1171978724000},"page":"5-11","source":"Crossref","is-referenced-by-count":8,"title":["Clinicopathological study of primary malignant tumors of the lung: An analysis of 993 tumors resected at the Kanazawa university hospital between 1979\u20101993"],"prefix":"10.1002","volume":"58","author":[{"given":"Akitaka","family":"Nonomura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Mizukami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junzo","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Oda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinya","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoh","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryoichi","family":"Kamimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsutomu","family":"Takashima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanobu","family":"Kitagawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_1_2","first-page":"837","volume-title":"Pathology of the Lung","author":"Spencer H","year":"1977"},{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/66.6.1192"},{"key":"e_1_2_1_3_2","first-page":"8","volume-title":"Cancer Facts and Figures, 1991","author":"American cancer society","year":"1991"},{"key":"e_1_2_1_4_2","first-page":"311","volume-title":"Pathology of the Lung","author":"Churg A","year":"1988"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4757-3935-0_32"},{"key":"e_1_2_1_6_2","first-page":"8","volume-title":"A Guide of Geriatric Diseases in 1994","author":"Japanese Anti\u2010Cancer Association","year":"1994"},{"key":"e_1_2_1_7_2","first-page":"25","article-title":"Regarding the reversal phenomenon of the mortality rate of lung and gastric cancer in Japanese males in the first half of the year 1993","volume":"41","author":"Ishii Y","year":"1994","journal-title":"J Health Welfare Statistics"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197704)39:4<1647::AID-CNCR2820390439>3.0.CO;2-H"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810301)47:5<1042::AID-CNCR2820470535>3.0.CO;2-5"},{"key":"e_1_2_1_10_2","volume-title":"Histological Typing of Lung Tumours. International Histological Classification of Tumours. No. 1","author":"Kreyberg L","year":"1981"},{"key":"e_1_2_1_11_2","first-page":"65","volume-title":"Morphogenesis of Lung Cancer","author":"Shimosato Y","year":"1982"},{"key":"e_1_2_1_12_2","volume-title":"TNM Classification of Malignant Tumours","author":"International Union Against Cancer","year":"1987"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1016458"},{"key":"e_1_2_1_14_2","first-page":"841","article-title":"A massive screening examination for lung cancer","volume":"8","author":"Ikeda S","year":"1978","journal-title":"J Adult Dis"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/jso.2930480202"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.41.3.137"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/81.20.1568"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/83.5.368-a"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19870515)59:10<1825::AID-CNCR2820591024>3.0.CO;2-2"},{"key":"e_1_2_1_20_2","first-page":"561","article-title":"Early lung cancer detection: Results of the initial (prevalence) radiologic and cytologic screening in the Memorial Sloan\u2010Kettering study","volume":"130","author":"Flechinger BJ","year":"1984","journal-title":"Am Rev Respir Dis"},{"key":"e_1_2_1_21_2","first-page":"561","article-title":"Early lung cancer detection: Results of the initial (prevalence) radiologic and cytologic screening in the Mayo Clinic study","volume":"130","author":"Fontana RS","year":"1985","journal-title":"Am Rev Respir Dis"},{"key":"e_1_2_1_22_2","first-page":"771","article-title":"Population distribution of histological types of lung cancer: Epidemiologic aspects in Israel and review of the literature","volume":"14","author":"Modan B","year":"1978","journal-title":"Isr J Med Sci"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910170305"},{"key":"e_1_2_1_24_2","first-page":"48","volume-title":"A Guide to Geriatric Diseases in 1994","author":"Japanese Anti\u2010Cancer Association","year":"1994"},{"key":"e_1_2_1_25_2","first-page":"1181","article-title":"Present status of and problems in the treatment of early lung cancer","volume":"19","author":"Yoneyama T","year":"1983","journal-title":"J Clin Sci"},{"key":"e_1_2_1_26_2","first-page":"40","article-title":"Prognostic evaluation of small sized lung cancer following surgery","volume":"24","author":"Tomita M","year":"1979","journal-title":"Acta Med Nagasaki"},{"key":"e_1_2_1_27_2","first-page":"663","article-title":"Prospective 5\u2010year disease\u2010free rate in patients with small peripheral adenocarcinoma of the lung with respect to histopathological findings","volume":"27","author":"Kurata M","year":"1987","journal-title":"Lung Cancer"},{"key":"e_1_2_1_28_2","first-page":"257","article-title":"Analysis of results of surgical treatment in patients with TINOMO lung cancer","volume":"27","author":"Nakahashi H","year":"1987","journal-title":"Lung Cancer"},{"key":"e_1_2_1_29_2","first-page":"944","article-title":"Analysis of patients with resected small\u2010sized (\u2a7e 2cm in diameter) peripheral type lung cancer lesions","volume":"28","author":"Sagawa M","year":"1990","journal-title":"Jpn J Thorac Dis"},{"key":"e_1_2_1_30_2","first-page":"869","article-title":"A clinical study in small sized lung cancer of peripheral type less than 2 cm in diameter","volume":"32","author":"Nishiyama H","year":"1992","journal-title":"Lung Cancer"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.2930580103","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.2930580103","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T18:45:38Z","timestamp":1698345938000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.2930580103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,1]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1995,1]]}},"alternative-id":["10.1002\/jso.2930580103"],"URL":"https:\/\/doi.org\/10.1002\/jso.2930580103","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,1]]}}}