{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T03:12:46Z","timestamp":1789269166410,"version":"build-2803163510"},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,7,26]],"date-time":"2025-07-26T00:00:00Z","timestamp":1753488000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Solid pseudopapillary tumors (SPTs) of the pancreas occur predominantly in young females and possess low malignant potential. In this study, clinicopathologic, perioperative, and long\u2010term outcomes are compared in SPT patients that received open or minimally invasive (MIS) resection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The National Cancer Database (2010\u20102020) was queried to identify all patients with SPTs that underwent an open or MIS surgical resection. Propensity score matching analysis was conducted through 1:1 matching based on the nearest neighbor method.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 835 patients, 59.7% received an open approach and 40.3% were performed MIS. Over the decade, MIS approach increased from 7.7% to 60.0% for distal pancreatectomy (DP) and 15.4% to 30.2% for pancreaticoduodenectomy (PD) (both <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). There were no differences in lymphadenectomy (&gt;15 nodes) or resection margin positivity. Shorter length of stay was noted for MIS resections (PD: 5 vs. 8 days, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001; DP: 5 vs. 6 days, <jats:italic>p<\/jats:italic>\u2009=\u20090.022), and no difference was appreciated in 30\u2010day readmission rates. There was no difference in overall survival between open and MIS approaches for PD and DP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Minimally invasive resections for SPTs have increased by ~40% over a decade and may offer a safe and feasible alternative to open resection that provides similar perioperative and long\u2010term oncologic outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.70054","type":"journal-article","created":{"date-parts":[[2025,7,26]],"date-time":"2025-07-26T09:36:54Z","timestamp":1753522614000},"page":"676-683","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Minimally Invasive Versus Open Resection for Solid Pseudopapillary Tumors of the Pancreas: A Propensity Score\u2010Matched Analysis"],"prefix":"10.1002","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5833-0331","authenticated-orcid":false,"given":"Paul","family":"Wong","sequence":"first","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery University of California San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Letizia","family":"Todeschini","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery University of California San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8036-5699","authenticated-orcid":false,"given":"Tommaso","family":"Pollini","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery University of California San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia","family":"Hernandez","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery University of California San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Zampese","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery University of California San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Laurean","family":"Aguilar","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery University of California San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"June S.","family":"Peng","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery University of California San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas W.","family":"Thornblade","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery University of California San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed A.","family":"Adam","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery University of California San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Alseidi","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery University of California San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos U.","family":"Corvera","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery University of California San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenzo","family":"Hirose","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery University of California San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly S.","family":"Kirkwood","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery University of California San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric K.","family":"Nakakura","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery University of California San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8234-2762","authenticated-orcid":false,"given":"Ajay V.","family":"Maker","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery University of California San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1007\/s12253-019-00671-8","article-title":"Solid\u2010Pseudopapillary Neoplasms of the Pancreas Is Still An Enigma: A Clinicopathological Review","volume":"26","author":"Zalatnai A.","year":"2020","journal-title":"Pathology & Oncology 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