{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T18:48:15Z","timestamp":1773600495062,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T00:00:00Z","timestamp":1771718400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T00:00:00Z","timestamp":1771718400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To test the effect of laterality on the risk of intraoperative complications (ICs) in a contemporary cohort of adrenalectomy patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Within the Nationwide Inpatient Sample (NIS) database (2015\u20132019), we identified patients who underwent either minimal\u2010invasive or open adrenalectomy. Multivariable logistic regression models tested for the association of laterality and IC. Additionally, this association was further tested in specific subgroups, namely patients with elevated body mass index (BMI)\u2009\u2265\u200930, patients who underwent minimal\u2010invasive adrenalectomy, and patients who underwent open adrenalectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, we identified 4887 patients who underwent adrenalectomy. Of those, 2143 (44%) were right\u2010sided, and 2744 (56%) left\u2010sided. An IC was recorded in 90 (1.8%) patients. Right\u2010sided adrenalectomy had significantly more IC compared to left\u2010sided adrenalectomy (2.6% vs. 1.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). After multivariable adjustment, right side emerged as an independent predictor for IC (OR 1.9,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007). In subgroup analysis, right\u2010side remained an independent predictor for IC in patients with BMI\u2009\u2265\u200930 (OR 4.08\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003) and minimal\u2010invasive adrenalectomy (OR 2.3\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01) patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>ICs in adrenalectomy are rare, but are associated with high morbidity. Right\u2010sided adrenalectomy carries an increased risk for IC. Conversely, surgeons should exercise particular caution when approaching the right adrenal gland to mitigate the associated risks and enhance patient outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jso.70195","type":"journal-article","created":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T17:30:29Z","timestamp":1771781429000},"page":"454-458","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Does Laterality Affect the Risk of Intraoperative Complications in Adrenalectomy?"],"prefix":"10.1002","volume":"133","author":[{"given":"Lukas","family":"Scheipner","sequence":"first","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Department of Urology Medical University of Graz Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5340-8569","authenticated-orcid":false,"given":"Simone","family":"Morra","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Department of Neurosciences, Science of Reproduction and Odontostomatology University of Naples Federico II Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Baudo","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Department of Urology IRCCS Policlinico San Donato Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Letizia Maria Ippolita","family":"Jannello","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Department of Urology IEO European Institute of Oncology, IRCCS Milan Italy"},{"name":"Universit\u00e0 degli Studi di Milano Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5460-4171","authenticated-orcid":false,"given":"Carolin","family":"Siech","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Department of Urology University Hospital Frankfurt, Goethe University Frankfurt am Main Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"de Angelis","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Division of Experimental Oncology\/Unit of Urology URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordan A.","family":"Goyal","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhe","family":"Tian","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fred","family":"Saad","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahrokh F.","family":"Shariat","sequence":"additional","affiliation":[{"name":"Department of Urology, Comprehensive Cancer Center Medical University of Vienna Vienna Austria"},{"name":"Department of Urology Weill Cornell Medical College New York New York USA"},{"name":"Department of Urology University of Texas Southwestern Dallas Texas USA"},{"name":"Hourani Center for Applied Scientific Research Al\u2010Ahliyya Amman University Amman Jordan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Briganti","sequence":"additional","affiliation":[{"name":"Division of Experimental Oncology\/Unit of Urology URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix K. H.","family":"Chun","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital Frankfurt, Goethe University Frankfurt am Main Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Longo","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Science of Reproduction and Odontostomatology University of Naples Federico II Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Carmignani","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli Studi di Milano Milan Italy"},{"name":"Department of Oncology and Haemato\u2010Oncology Universit\u00e0 degli Studi di Milano Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ottavio","family":"De Cobelli","sequence":"additional","affiliation":[{"name":"Department of Urology IEO European Institute of Oncology, IRCCS Milan Italy"},{"name":"Department of Oncology and Haemato\u2010Oncology Universit\u00e0 degli Studi di Milano Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maximilian","family":"Seles","sequence":"additional","affiliation":[{"name":"Department of Urology Medical University of Graz Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Mischinger","sequence":"additional","affiliation":[{"name":"Department of Urology Medical University of Graz Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sascha","family":"Ahyai","sequence":"additional","affiliation":[{"name":"Department of Urology Medical University of Graz Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre I.","family":"Karakiewicz","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,22]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"161","article-title":"Complications Following Adrenal Surgery","volume":"83","author":"McLeod M. 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