{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T03:30:06Z","timestamp":1792207806854,"version":"4.4.0"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100012604","name":"Crown Family Philanthropies","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012604","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Native Hawaiian and Pacific Islander (NHPI) populations face significant disparities in cervical cancer prevention and treatment. This systematic review and meta\u2010analysis examines cervical cancer prevention metrics, treatment disparities, and effective interventions among NHPI populations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Following PRISMA guidelines, we systematically searched PubMed, Scopus, and Embase for studies published between 2000 and 2024 that reported cervical cancer prevention metrics in NHPI populations. Eligible studies included quantitative and qualitative designs with NHPI\u2010specific or disaggregated data. Pap testing and HPV vaccination rates were pooled using a random\u2010effects meta\u2010analysis. Narrative synthesis summarized findings from studies unsuitable for meta\u2010analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 27 studies were included. The pooled Pap testing rate was 62% (95% CI: 46%\u201375%), with substantial heterogeneity (I\u00b2 = 98.7%). The pooled HPV vaccine initiation rate was 25% (95% CI: 16%\u201337%; I\u00b2 = 84.3%). Barriers included limited healthcare access, lack of physician recommendations, cultural stigma, and geographic isolation. Effective interventions, such as culturally tailored educational materials and community\u2010based participatory approaches, demonstrated improved screening and vaccination rates. NHPI patients were less likely to receive timely and guideline\u2010concordant cervical cancer treatment and had higher rates of late\u2010stage diagnoses and mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>NHPI populations face persistent cervical cancer prevention and treatment disparities. Culturally tailored interventions and policies addressing systemic barriers are critical to reducing these inequities. Future research should focus on longitudinal studies and scalable interventions to improve outcomes in NHPI communities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jso.70200","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T07:05:59Z","timestamp":1769670359000},"page":"590-606","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cervical Cancer Prevention and Treatment Disparities Among Native Hawaiian and Pacific Islanders: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1002","volume":"133","author":[{"given":"Antoinette T.","family":"Nguyen","sequence":"first","affiliation":[{"name":"University of Rochester School of Medicine and Dentistry Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily D.","family":"Duckworth","sequence":"additional","affiliation":[{"name":"University of South Carolina School of Medicine 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