{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T03:46:36Z","timestamp":1791863196095,"version":"4.3.4"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T00:00:00Z","timestamp":1779580800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T00:00:00Z","timestamp":1779580800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Methods<\/jats:title>\n                    <jats:p>Venous thromboembolism (VTE) is common and preventable following surgery for gastrointestinal (GI) cancer. In this retrospective cohort study, we aimed to characterize VTE risk factors, prophylaxis, and outcomes among patients who underwent surgery for GI cancer between 2019 and 2021 at Kaiser Permanente Southern California. The discrimination of the Caprini and IMPROVE risk models for predicting VTE was assessed using the area under the receiver operating characteristic curve (AUC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 2702 patients, the 90\u2010day incidence of perioperative VTE was 2.1%. VTE was associated with older age, prior VTE, thrombophilia, low serum albumin, and blood transfusion, but not procedure time or surgical approach. VTE was especially common among patients with gastric cancer (4.5%). In\u2010hospital prophylaxis was nearly universal, but post\u2010discharge prophylaxis was uncommonly utilized (22.9%). VTE was associated with a five\u2010fold increase in 90\u2010day mortality. Both Caprini (AUC 0.65, 95% CI 0.57\u20100.72) and IMPROVE (AUC 0.65, 95% CI 0.57\u20130.73) models demonstrated only fair discrimination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Despite adherence with recommended in\u2010hospital prophylaxis, VTE remains an important complication following GI cancer surgery, carrying with it an increased risk of mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Suboptimal discrimination of risk prediction models and underutilization of post\u2010discharge prophylaxis represent ongoing opportunities for quality improvement.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jso.70290","type":"journal-article","created":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T18:55:18Z","timestamp":1779648918000},"page":"248-256","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Venous Thromboembolism Risk and Prevention After Gastrointestinal Cancer Surgery: Real World Evidence From a Large Integrated Healthcare System"],"prefix":"10.1002","volume":"134","author":[{"given":"Tong","family":"Qi","sequence":"first","affiliation":[{"name":"Kaiser Permanente Bernard J. Tyson School of Medicine Pasadena California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In\u2010Lu Amy","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation Kaiser Permanente Southern California Pasadena California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010Lin","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation Kaiser Permanente Southern California Pasadena California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacy J.","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation Kaiser Permanente Southern California Pasadena California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed N.","family":"Dehal","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation Kaiser Permanente Southern California Pasadena California USA"},{"name":"Department of Clinical Science Kaiser Permanente Bernard J. Tyson School of Medicine Pasadena California USA"},{"name":"Department of Surgery Southern California Permanente Medical Group Panorama City California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael K.","family":"Gould","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation Kaiser Permanente Southern California Pasadena California USA"},{"name":"Department of Health Systems Science Kaiser Permanente Bernard J. Tyson School of Medicine Pasadena California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000078469.07362.E6"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000193959.44677.48"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004318.pub5"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2010.03892.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0305-7372(02)00043-9"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2297"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.59.7351"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2019000975"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2016.03.023"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.27473"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.disamonth.2005.02.003"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-1944"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.7812\/TPP\/12-031"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/1536867X0900900101"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2021.06.010"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31821b98da"},{"issue":"6","key":"e_1_2_8_18_1","first-page":"267","article-title":"Thromboembolism in Gastrointestinal Cancers","volume":"2","author":"Tetzlaff E. 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