{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:14:06Z","timestamp":1788279246860,"version":"build-2803163510"},"reference-count":71,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:00:00Z","timestamp":1781740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:00:00Z","timestamp":1781740800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Multimodal prehabilitation aims to improve surgical outcomes and preoperative fitness in patients undergoing surgery for colorectal cancer (CRC). This study evaluated implementation of a standardised prehabilitation programme for elective CRC surgery, assess its impact, and identify pitfalls and challenges during implementation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective single\u2010centre study, all CRC patients scheduled for resection between January 2022 and April 2024 were included. Since May 2023, standardised multimodal prehabilitation was introduced. Before, patients received physiotherapy and a dietician if indicated, although this was not routinely offered. Patients were divided into a prehabilitation and non\u2010prehabilitation group. Clinical data, prehabilitation details, and physiotherapy results were collected from patient charts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 401 patients, 198 (49%) underwent prehabilitation. Participation increased after standardisation (40% vs. 59%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Strength and physical fitness improved significantly (leg press 100 vs. 135\u2009kg; steep ramp 160 vs. 213\u2009W;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Patients in the non\u2010standardised programme experienced a significantly longer postoperative hospital stay than those in standardised programme (4 vs. 3 days,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.010). Despite more comorbidities in prehabilitated patients, complication rates were similar between patients without and with prehabilitation (28% vs. 24%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.45).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Standardised prehabilitation appears beneficial and safe, improving participation, referral justification and outcomes, particularly in high\u2010risk colorectal cancer patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jso.70305","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T10:30:09Z","timestamp":1781778609000},"page":"434-443","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prehabilitation Prior to Colorectal Cancer Surgery: Impact and Implementation"],"prefix":"10.1002","volume":"134","author":[{"given":"Elize W.","family":"Lockhorst","sequence":"first","affiliation":[{"name":"Department of Surgery Amphia Hospital Breda Breda The Netherlands"},{"name":"Department of Surgical Oncology and Gastrointestinal Surgery Erasmus MC University Cancer Institute Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresia A. 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