{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T06:13:18Z","timestamp":1788502398791,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Glossectomy for oral cancer can lead to significant concerns regarding speech and swallowing function. This study aims to assess the impact of age on post\u2010glossectomy functional recovery and quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective analysis of patients who underwent glossectomy for primary oral cavity cancer involving the oral tongue from 2016 to 2024. Patients were stratified into three cohorts: &lt;\u200960, 60\u201370, and &gt;\u200970 years. Functional outcomes were assessed using speech\u2010language pathology evaluations at 1 month, 6 months, 1 year, and 2 years postoperatively. Patient\u2010reported quality of life was assessed using FACE\u2010Q scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      206 patients were included, with 92 patients under 60, 61 patients aged 60\u201370, and 53 patients over 70. Primary closure was performed in 80 patients (39%), and free flap reconstruction in 109 (53%). One month postoperatively, patients over 70 demonstrated significantly higher rates of moderate to severe reductions in labial ROM and strength (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). At 1 and 2 years, most functional differences had resolved, but deficits in labial ROM and strength persisted at 2 years (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.048). FACE\u2010Q scores, gastrostomy tube and tracheostomy dependence, length of stay, readmission, reoperation, and revision rates did not differ across cohorts. When adjusting for comorbidities, glossectomy type and age were significant predictors of long\u2010term functional outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Older patients undergoing glossectomy may experience initial delays in functional recovery, but long\u2010term clinically meaningful functional outcomes are comparable across age groups. However, older patients may experience decreased patient\u2010reported satisfaction in key domains, emphasizing the need for careful patient selection and shared decision\u2010making when considering glossectomy in older adults.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jso.70355","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T05:35:45Z","timestamp":1788500145000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Impact of Advanced Age on Functional Recovery Following Glossectomy"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4146-1826","authenticated-orcid":false,"given":"Jenny","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery Memorial Sloan Kettering Cancer Center New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayana","family":"Cole\u2010Price","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Memorial Sloan Kettering Cancer Center New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5465-4230","authenticated-orcid":false,"given":"Brianna M.","family":"Peet","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Memorial Sloan Kettering Cancer Center New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9070-9296","authenticated-orcid":false,"given":"Kyeong\u2010Tae","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Memorial Sloan Kettering Cancer Center New York New York USA"},{"name":"Department of Plastic Surgery Samsung Medical Center Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey E.","family":"Hespe","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Memorial Sloan Kettering Cancer Center New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lillian A.","family":"Boe","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics Memorial Sloan Kettering Cancer Center New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Cunningham","sequence":"additional","affiliation":[{"name":"Department of Speech and Language Pathology Memorial Sloan Kettering Cancer Center New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7758-8015","authenticated-orcid":false,"given":"Farooq","family":"Shahzad","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Memorial Sloan Kettering Cancer Center New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6104-7967","authenticated-orcid":false,"given":"Marc A.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Surgery Head and Neck Service,Memorial Sloan Kettering Cancer Center New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4496-906X","authenticated-orcid":false,"given":"Jennifer R.","family":"Cracchiolo","sequence":"additional","affiliation":[{"name":"Department of Surgery Head and Neck Service,Memorial Sloan Kettering Cancer Center New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas A.","family":"Nelson","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Memorial Sloan Kettering Cancer Center New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan","family":"Matros","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Memorial Sloan Kettering Cancer Center New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Robert J.","family":"Allen","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Memorial Sloan Kettering Cancer Center New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2008.06.002"},{"key":"e_1_2_9_3_1","unstructured":"Oral Cancer National Institute of Dental and Craniofacial Research Accessed December 16 2024 https:\/\/www.nidcr.nih.gov\/health-info\/oral-cancer."},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41368-023-00249-w"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006386.pub4"},{"key":"e_1_2_9_6_1","volume-title":"StatPearls","author":"Bigcas J. 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