{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T06:50:06Z","timestamp":1792047006558,"version":"4.4.0"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Adjuvant radiotherapy (RT) following breast\u2010conserving surgery reduces local recurrence but can introduce reconstructive morbidity. Although recent trials support the safe omission of RT in selected patients, its impact on surgical and patient\u2010reported outcomes following oncoplastic breast\u2010conserving surgery (OPBCS) remains poorly defined. We evaluated surgical and long\u2010term patient\u2010reported outcomes in patients undergoing OPBCS, stratified by receipt of RT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively studied consecutive patients who underwent OPBCS between 2017 and 2024 for stage 0\u20133 breast cancer. Patients were stratified based on receipt of RT. Postoperative complications, unplanned reoperation, and revision procedures were compared between cohorts. Long\u2010term patient\u2010reported outcomes were assessed using the validated BREAST\u2010Q Reconstruction Module. Multivariable regression was used to evaluate the independent association between RT status and outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We identified 257 patients; 210 patients received RT (81.7%) and 47 underwent RT de\u2010escalation (18.3%). Surgical site infection (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.100), delayed wound healing (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.300), and skin flap necrosis rates (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0300) were similar between cohorts. Seroma (30% vs. 13%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006) and unplanned reoperation (21% vs. 7.1%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006) were more frequent with RT omission. Patients who did not receive RT demonstrated significantly higher mean Satisfaction with Breasts scores compared with those who received RT (57\u2009\u00b1\u200925 vs. 23\u2009\u00b1\u200924;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). In adjusted models, RT de\u2010escalation was associated with a 36\u2010point increase in Satisfaction with Breasts scores (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u200936.0; 95% CI, 18.0\u201354.0;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>RT omission was independently associated with higher patient\u2010reported satisfaction with breasts, though patients had higher seroma and reoperation rates. These data support balanced shared decision\u2010making for RT de\u2010escalation in appropriately selected patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jso.70425","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T06:41:39Z","timestamp":1792046499000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association of Adjuvant Radiotherapy De\u2010Escalation With Outcomes Following Oncoplastic Breast\u2010Conserving Surgery"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1070-0524","authenticated-orcid":false,"given":"Abbas M.","family":"Hassan","sequence":"first","affiliation":[{"name":"Division of Plastic Surgery, Department of Surgery Indiana University School of Medicine Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9284-9303","authenticated-orcid":false,"given":"Carson","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Department of Surgery Indiana University School of Medicine Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5336-4310","authenticated-orcid":false,"given":"Kathryn","family":"Borders","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Department of Surgery Indiana University School of Medicine Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel M.","family":"Danforth","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Department of Surgery Indiana University School of Medicine Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravinder","family":"Bamba","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Department of Surgery Indiana University School of Medicine Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Jason VonDerHaar","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Department of Surgery Indiana University School of Medicine Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0832-5537","authenticated-orcid":false,"given":"Ivan","family":"Hadad","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Department of Surgery Indiana University School of Medicine Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2953-7373","authenticated-orcid":false,"given":"Mary E.","family":"Lester","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Department of Surgery Indiana University School of Medicine Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla S.","family":"Fisher","sequence":"additional","affiliation":[{"name":"Division of Breast Surgery, Department of Surgery Indiana University School of Medicine Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0966-7851","authenticated-orcid":false,"given":"Aladdin H.","family":"Hassanein","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Department of Surgery Indiana University School of Medicine Indianapolis Indiana 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