{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T19:04:24Z","timestamp":1783796664968,"version":"3.55.0"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T00:00:00Z","timestamp":1622073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JOR Spine"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the three\u2010dimensional (3D) changes of the spinal canal length (SCL) after corrective surgeries and their association with the radiographic and clinical outcomes of idiopathic scoliosis patients. The length of the spinal cord has been demonstrated to be strongly correlated with the SCL. Understanding the changes in SCL could help determine the morphologic changes in the spinal cord to prevent spinal cord injury.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010seven scoliotic patients' 3D spinal canal were investigated using computed tomography images. The SCL between the upper and lower end vertebrae (U\/L\u2010EV) was measured at five locations. The radiographic parameters of each patient and the patient\u2010reported outcomes (PROs) scores were also collected. The correlations of the changes of the SCLs with the other factors were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The SCL between the U\/L\u2010EV changed non\u2010uniformly at different locations. The post\u2010operative SCLs were significantly elongated by 7.5\u2009\u00b1\u20093.5\u2009mm (6.0\u2009\u00b1\u20092.5%, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001) at the concave side and compressed by \u22122.6\u2009\u00b1\u20092.6\u2009mm (\u22121.9\u2009\u00b1\u20091.9%, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001) at the convex side. The elongations of the SCL at the concave and posterior locations were correlated with the radiographic parameters including the pre\u2010operative main Cobb angles (<jats:italic>r<\/jats:italic>\u00a0=\u00a0.511, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.006; <jats:italic>r<\/jats:italic>\u00a0=\u00a0.613, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.001) and apical vertebral translation (AVT) (<jats:italic>r<\/jats:italic>\u00a0=\u00a0.481, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.011; <jats:italic>r<\/jats:italic>\u00a0=\u00a0.684, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.000). No PRO scores were found to correlate with the SCL changes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The corrective surgeries elongated the spinal canal mainly at the concave side and compressed at the convex side. The main thoracic Cobb angle, the changes of AVT, and Cobb angles were moderately associated with the changes of the SCLs, but no PRO score was found to associate with the changes of the SCLs. The data could be instrumental for the improvement of corrective surgeries that are aimed to maximize the correction of scoliosis and minimize the negative effect on the spinal cord to prevent neurological complications.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsp2.1151","type":"journal-article","created":{"date-parts":[[2021,5,28]],"date-time":"2021-05-28T00:36:29Z","timestamp":1622162189000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Investigation of in vivo three\u2010dimensional changes of the spinal canal after corrective surgeries of the idiopathic scoliosis"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3893-2570","authenticated-orcid":false,"given":"Chaofan","family":"Han","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Beijing Chao\u2010Yang Hospital, Capital Medical University  Beijing China"},{"name":"Department of Orthopaedic Surgery, Bioengineering Research Center Newton\u2010Wellesley Hospital, Harvard Medical School  Newton Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Hai","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Beijing Chao\u2010Yang Hospital, Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2631-2622","authenticated-orcid":false,"given":"Chaochao","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Bioengineering Research Center Newton\u2010Wellesley Hospital, Harvard Medical School  Newton Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Beijing Chao\u2010Yang Hospital, Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Runsheng","family":"Guo","sequence":"additional","affiliation":[{"name":"First Affiliated Hospital of Nanchang University  Nanchang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiming","family":"Wang","sequence":"additional","affiliation":[{"name":"Nanfang Hospital  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Beihang University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Cha","sequence":"additional","affiliation":[{"name":"Orthopaedic Spine Center Massachusetts General Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Bioengineering Research Center 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