{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T02:42:28Z","timestamp":1790131348923,"version":"4.0.1"},"reference-count":104,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JOR Spine"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>In parallel with population aging, the prevalence of neurological and neurodegenerative diseases has been dramatically increasing over the past few decades. Neurodegenerative diseases reduce the quality of life of patients and impose a high cost on the health system. These slowly progressive diseases can cause functional, perceptual, and behavioral deficits in patients. Therefore, neurodegenerative impairments have always been an interesting subject for scientists and clinicians. One of these diseases is spinal cord injury (SCI). SCI can lead to irreversible damage and is classified into two main subtypes: traumatic and non\u2010traumatic, each with very different pathophysiological features.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>This review aims to gather relevant information about the beneficial effects of curcumin (Cur), with specific emphasis on its anti\u2010inflammatory properties towards spinal cord injury (SCI) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials &amp; Methods<\/jats:title><jats:p>The review collates data from extensive in\u2010vitro, in\u2010vivo, and clinical trials documenting the effects of CUR on SCI. It examines the modulation of pathophysiological pathways and regulation of the inflammatory cascades after CUR administration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Various pathophysiological processes involving the nuclear factor erythroid 2\u2010related factor 2 (Nrf2), nuclear factor kappa B (NF\u2010kB), and transforming growth factor beta (TGF\u2010\u03b2) signaling pathways have been suggested to exacerbate damages resulting from SCI. CUR administration showed to modulate these signaling pathways which lead to attenuation of SCI complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Anti\u2010inflammatory compounds, particularly CUR, can modulate these pathophysiological pathways and regulate the inflammatory cascades. CUR, a well\u2010known natural product with significant anti\u2010inflammatory effects, has been extensively documented in experimental and clinical trials.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Curcumin's potential to alter key steps in the Nrf2, NF\u2010kB, and TGF\u2010\u03b2 signaling pathways suggests that it may play a role in attenuating SCI complications.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsp2.1364","type":"journal-article","created":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T10:19:38Z","timestamp":1723630778000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Protective effects of curcumin against spinal cord injury"],"prefix":"10.1002","volume":"7","author":[{"given":"Seyed Mehrad","family":"Razavi","sequence":"first","affiliation":[{"name":"Department of Toxicology &amp; Pharmacology, Faculty of Pharmacy, Tehran Medical Sciences Islamic Azad University  Tehran Iran"},{"name":"GI Pharmacology Interest Group (GPIG) Universal Scientific Education and Research Network (USERN)  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danial","family":"Khayatan","sequence":"additional","affiliation":[{"name":"Department of Toxicology &amp; Pharmacology, Faculty of Pharmacy, Tehran Medical Sciences Islamic Azad University  Tehran Iran"},{"name":"GI Pharmacology Interest Group (GPIG) Universal Scientific Education and Research Network (USERN)  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Najafi Arab","sequence":"additional","affiliation":[{"name":"Department of Toxicology &amp; Pharmacology, Faculty of Pharmacy, Tehran Medical Sciences Islamic Azad University  Tehran Iran"},{"name":"GI Pharmacology Interest Group (GPIG) Universal Scientific Education and Research Network (USERN)  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasamin","family":"Hosseini","sequence":"additional","affiliation":[{"name":"Department of Toxicology &amp; Pharmacology, Faculty of Pharmacy, Tehran Medical Sciences Islamic Azad University  Tehran Iran"},{"name":"GI Pharmacology Interest Group (GPIG) Universal Scientific Education and Research Network (USERN)  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Khanahmadi","sequence":"additional","affiliation":[{"name":"Department of Toxicology &amp; Pharmacology, Faculty of Pharmacy, Tehran Medical Sciences Islamic Azad University  Tehran Iran"},{"name":"GI Pharmacology Interest Group (GPIG) Universal Scientific Education and Research Network (USERN)  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeideh","family":"Momtaz","sequence":"additional","affiliation":[{"name":"Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR  Karaj Iran"},{"name":"Department of Toxicology and Pharmacology School of Pharmacy, and Toxicology and Diseases Group, Pharmaceutical Sciences Research Center (PSRC), The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tannaz","family":"Jamialahmadi","sequence":"additional","affiliation":[{"name":"Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences  Mashhad Iran"},{"name":"Medical Toxicology Research Center, Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas P.","family":"Johnston","sequence":"additional","affiliation":[{"name":"Division of Pharmacology and Pharmaceutical Sciences School of Pharmacy, University of Missouri\u2010Kansas City  Kansas City Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir Hossein","family":"Abdolghaffari","sequence":"additional","affiliation":[{"name":"Department of Toxicology &amp; Pharmacology, Faculty of Pharmacy, Tehran Medical Sciences Islamic Azad University  Tehran Iran"},{"name":"GI Pharmacology Interest Group (GPIG) Universal Scientific Education and Research Network (USERN)  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8656-1444","authenticated-orcid":false,"given":"Amirhossein","family":"Sahebkar","sequence":"additional","affiliation":[{"name":"Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences  Mashhad Iran"},{"name":"Applied Biomedical Research Center, Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2567.2009.03225.x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2017.18"},{"issue":"11","key":"e_1_2_10_4_1","first-page":"2223","article-title":"The change tendency of PI3K\/Akt pathway after spinal cord injury","volume":"7","author":"Zhang P","year":"2015","journal-title":"Am J Trans Res"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4353-06.2007"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000146962.91038.15"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.2174\/1871527319666200604175118"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2018.00690"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules23102485"},{"key":"e_1_2_10_10_1","volume":"2019","author":"Coyoy\u2010Salgado A, Segura\u2010Uribe JJ, Guerra\u2010Araiza C","journal-title":"Oxid Med Cell Longev"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eujim.2020.101252"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/CEJ.0b013e32832c389e"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.26249"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.26538"},{"key":"e_1_2_10_15_1","volume":"147","author":"Shafabakhsh R, Pourhanifeh MH, Mirzaei HR, Sahebkar A, Asemi Z, Mirzaei H","journal-title":"Pharmacol Res"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.27096"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/biof.1566"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-019-01916-7"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.27362"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2022.106414"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24224029"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.7737"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcme.2016.08.002"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10787-019-00607-3"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2018.12.005"},{"key":"e_1_2_10_26_1","volume":"49","author":"Saberi\u2010Karimian M, Keshvari M, Ghayour\u2010Mobarhan M","journal-title":"Complement Ther Med"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10571-019-00671-x"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1955"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2008.04.038"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2013.11.002"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12017-019-08585-z"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3053"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10571-016-0422-8"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.21508"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200405010-00004"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.jnen.0000248552.07338.7f"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/3-540-32636-7_1"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.imbio.2015.05.013"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2013.5453"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2005.7.385"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2016.12.014"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2020.115014"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2023.156206"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15112895"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2016.96"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.2174\/1872213X12666180703163824"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.3390\/nano11010002"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2015.09.004"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S199624"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics12050476"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.4103\/2221-1691.328058"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.3390\/nano10091650"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S208332"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S327737"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2022.121287"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24108874"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24234386"},{"key":"e_1_2_10_58_1","first-page":"49","volume-title":"Chapter 2. Elucidating the Structure\u2013Activity Relationship of Curcumin and its Biological Activities","author":"Nantasenamat C","year":"2014"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1093\/advances\/nmx011"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2891-13-11"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2020.e05469"},{"issue":"13","key":"e_1_2_10_62_1","first-page":"1741","article-title":"Regulation of gene expression through food\u2010curcumin as a Sirtuin activity modulator","volume":"11","author":"Ungurianu A","year":"2022","journal-title":"Plants (Basel)"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/bmc.4267"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s43440-021-00312-5"},{"key":"e_1_2_10_65_1","first-page":"682","article-title":"Tissue distribution & elimination of capsaicin, piperine & curcumin following oral intake in rats","volume":"131","author":"Suresh D","year":"2010","journal-title":"Indian J Med Res"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2021.05.022"},{"key":"e_1_2_10_67_1","first-page":"1241","article-title":"Curcumin improves human umbilical cord\u2010derived mesenchymal stem cell survival via ERK1\/2 signaling and promotes motor outcomes after spinal cord injury","volume":"1","author":"Wanjiang W","year":"2020","journal-title":"Cell Mol Neurobiol"},{"key":"e_1_2_10_68_1","doi-asserted-by":"crossref","first-page":"9801","DOI":"10.12659\/MSM.918237","article-title":"Curcumin alleviates lipopolysaccharide (LPS)\u2010activated neuroinflammation via modulation of miR\u2010199b\u20105p\/I\u03baB kinase \u03b2 (IKK\u03b2)\/nuclear factor kappa B (NF\u2010\u03baB) pathway in microglia","volume":"25","author":"Gao F","year":"2019","journal-title":"Med Sci Monitor: Int Med J Exp Clin Res"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2011.1768"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2009.07.001"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.3340\/jkns.2017.0203.003"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2016.11.002"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1080\/10790268.2019.1616147"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-014-0710-z"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharep.2017.02.012"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.23729"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2019.05.018"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-010-0702-x"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2014.12.055"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2013.12.023"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1179\/2045772313Y.0000000179"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2013.11.050"},{"issue":"36","key":"e_1_2_10_83_1","first-page":"3391","article-title":"Curcumin protects against ischemic spinal cord injury: the pathway effect","volume":"8","author":"Zhang J","year":"2013","journal-title":"Neural Regen Res"},{"issue":"2","key":"e_1_2_10_84_1","first-page":"189","article-title":"Effect of curcumin on lipid peroxidation, early ultrastructural findings and neurological recovery after experimental spinal cord contusion injury in rats","volume":"22","author":"Sanli AM","year":"2012","journal-title":"Turk Neurosurg"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2019.07.013"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.3171\/2013.12.SPINE1312"},{"key":"e_1_2_10_87_1","doi-asserted-by":"publisher","DOI":"10.1179\/2045772312Y.0000000028"},{"key":"e_1_2_10_88_1","doi-asserted-by":"publisher","DOI":"10.21307\/ane-2018-035"},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-020-03174-0"},{"key":"e_1_2_10_90_1","doi-asserted-by":"publisher","DOI":"10.3171\/2012.1.SPINE11769"},{"issue":"5","key":"e_1_2_10_91_1","first-page":"3681","article-title":"Tetrahydrocurcumin protects against spinal cord injury and inhibits the oxidative stress response by regulating FOXO4 in model rats","volume":"18","author":"Xi J","year":"2019","journal-title":"Exp Ther Med"},{"key":"e_1_2_10_92_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17010049"},{"key":"e_1_2_10_93_1","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.oa.2013-0251"},{"key":"e_1_2_10_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2015.08.036"},{"key":"e_1_2_10_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2022.05.026"},{"key":"e_1_2_10_96_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11481-023-10081-y"},{"key":"e_1_2_10_97_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13578-022-00765-y"},{"key":"e_1_2_10_98_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10571-020-01018-7"},{"issue":"12","key":"e_1_2_10_99_1","first-page":"1241","article-title":"A hyaluronic acid demilune scaffold and Polypyrrole\u2010coated fibers carrying embedded human neural precursor cells and curcumin for surface capping of spinal cord injuries","volume":"9","author":"Elkhenany H","year":"2021","journal-title":"Biomedicine"},{"key":"e_1_2_10_100_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13770-023-00567-4"},{"key":"e_1_2_10_101_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-024-01539-4"},{"key":"e_1_2_10_102_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22115966"},{"key":"e_1_2_10_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2018.03.081"},{"key":"e_1_2_10_104_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-016-0625-4"},{"key":"e_1_2_10_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2021.103274"}],"container-title":["JOR SPINE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jsp2.1364","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T05:02:09Z","timestamp":1727326929000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jsp2.1364"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,14]]},"references-count":104,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1002\/jsp2.1364"],"URL":"https:\/\/doi.org\/10.1002\/jsp2.1364","archive":["Portico"],"relation":{},"ISSN":["2572-1143","2572-1143"],"issn-type":[{"value":"2572-1143","type":"print"},{"value":"2572-1143","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,14]]},"assertion":[{"value":"2024-02-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e1364"}}