{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:42:34Z","timestamp":1760920954438,"version":"build-2065373602"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,3,14]],"date-time":"2006-03-14T00:00:00Z","timestamp":1142294400000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Separation Science"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The use of a fluorogenic, hydrophilic, and amine\u2010reactive reagent, 2,6\u2010dimethyl\u20104\u2010quinolinecarboxylic acid <jats:italic>N<\/jats:italic>\u2010hydroxysuccinimide ester (DMQC\u2010OSu) has been investigated in the procolumn derivatization for the LC separation of aliphatic amines. In pH 8.0 aqueous medium, DMQC\u2010OSu reacted with amines at 50\u00b0C within 20 min to form highly fluorescent carboxamides and the excess reagent hydrolyzed to the corresponding carboxylic acid. The separation of representative amine derivatives with DMQC\u2010OSu has been performed using a C<jats:sub>18<\/jats:sub> column with the fluorescence detection at 326\/409 nm. The detection limits reached nanomolar level. The proposed method has been applied to the analysis of real samples with recoveries of 94\u2013108%. Compared with other succinimidyl esters used in the derivatization of amino compounds, DMQC\u2010OSu and its hydrolysate had negligible fluorescence (\u03d5\u00a0<jats:sub>fl <\/jats:sub>= 0.09 and 0.02, respectively), which implied that small peaks appeared in chromatograms and slight interference was introduced to the determination.<\/jats:p>","DOI":"10.1002\/jssc.200500508","type":"journal-article","created":{"date-parts":[[2006,3,14]],"date-time":"2006-03-14T12:48:34Z","timestamp":1142340514000},"page":"635-640","source":"Crossref","is-referenced-by-count":7,"title":["2,6\u2010Dimethyl\u20104\u2010quinolinecarboxylic acid <i>N<\/i>\u2010hydroxysuccinimide ester: A fluorogenic hydrophilic derivatizing reagent for liquid chromatographic analysis of aliphatic amines"],"prefix":"10.1002","volume":"29","author":[{"given":"Hong","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li\u2010Wei","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua\u2010Shan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,3,14]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/s0021663550164","volume":"355","author":"Pietsch J.","year":"1996","journal-title":"Fresenius J. 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