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For modeling, the number of peaks was used as a measure of fingerprint information. The optimum compositions of solvent to extract chemical substances from green tea and for mobile phase chromatographic analysis were ethyl acetate\/ethanol\/dichloromethane (20:5:75 v\/v\/v) and MeOH\/ACN\/water (7.5:57.5:35 v\/v\/v), respectively. This system results in 26 peaks in the chromatographic fingerprint. These results show that an incorrect choice of modifiers for mobile phase composition and solvent extraction hampers the detection of a maximum number of peaks and produces a poor chromatographic fingerprint.<\/jats:p>","DOI":"10.1002\/jssc.200600321","type":"journal-article","created":{"date-parts":[[2007,2,13]],"date-time":"2007-02-13T07:20:49Z","timestamp":1171351249000},"page":"414-420","source":"Crossref","is-referenced-by-count":23,"title":["Statistical mixture design optimization of extraction media and mobile phase compositions for the characterization of green tea"],"prefix":"10.1002","volume":"30","author":[{"given":"Aline","family":"Alves de Almeida","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ieda","family":"Spacino Scarminio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,2,13]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-199911000-00011"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1570-0232(04)00647-6"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2005.04.026"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/359594a0"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2005.04.008"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2005.01.035"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2003.12.049"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(02)00704-5"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.2116\/analsci.21.1019"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-4168(19981001)21:10<569::AID-JHRC569>3.0.CO;2-R"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-39709"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/chromsci\/41.5.241"},{"key":"e_1_2_1_14_2","unstructured":"Wijesekera R. 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