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In a second synthetic step, chemical derivatization of the activated\u2010ester moieties was performed<jats:italic> in situ<\/jats:italic> through alkylation reaction with alkylamines to afford monolithic stationary phases with potential reversed\u2010phase properties. A correlation between the synthesis conditions \u2013 <jats:italic>composition of the reactive solution<\/jats:italic> \u2013 chemical characteristics of the reactive polymer monoliths \u2013<jats:italic> nitrogen\/NAS content<\/jats:italic> \u2013 and the reversed\u2010phase separation properties of the functionalized monolithic columns \u2013 <jats:italic>selectivity towards homologous series of akylbenzenes<\/jats:italic> \u2013 was clearly established. This finding offers the possibility of adjusting the experimental conditions with respect to the target applications. The monolithic stationary phases with optimized chemical and porous structures were used for the CEC separation of alkylbenzenes, phenols, anilines, organic acids, amino acids, and proteins. The data indicate that depending on the nature of the analytes (charge, hydrophobic\/hydrophilic balance, size) reversed\u2010phase or mixed modes may account for the observed separation.<\/jats:p>","DOI":"10.1002\/jssc.200700384","type":"journal-article","created":{"date-parts":[[2007,10,26]],"date-time":"2007-10-26T02:44:20Z","timestamp":1193366660000},"page":"3000-3010","source":"Crossref","is-referenced-by-count":31,"title":["CEC separation of aromatic compounds and proteins on hexylamine\u2010functionalized <i>N<\/i>\u2010acryloxysuccinimide monoliths"],"prefix":"10.1002","volume":"30","author":[{"given":"Benjamin","family":"Carbonnier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Guerrouache","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renaud","family":"Denoyel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010Claude","family":"Millot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,11,21]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1111\/j.1438-8677.1906.tb06524.x","volume":"24","author":"Tswett M.","year":"1906","journal-title":"Ber. 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