{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:41:29Z","timestamp":1760920889405,"version":"build-2065373602"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,2,12]],"date-time":"2008-02-12T00:00:00Z","timestamp":1202774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Separation Science"],"published-print":{"date-parts":[[2008,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report the application of column temperature programs as a tool to examine unusual temperature\u2010induced behaviors of polysaccharide chiral stationary phases (CSPs). Using dihydropyrimidinone (DHP) compounds as probes we observed the heating (10\u201350\u00b0C) and cooling (50\u201310\u00b0C) van't Hoff plots of retention factors and\/or selectivities of DHP compounds were not superimposable on AD, IA, and AS\u2010H columns solvated with ethanol (EtOH)\/<jats:italic>n<\/jats:italic>\u2010hexane (<jats:italic>n<\/jats:italic>\u2010Hex) mobile phases. The plots were not superimposable on AD, IB, and AS\u2010H columns solvated with 2\u2010propanol (2\u2010PrOH)\/<jats:italic>n<\/jats:italic>\u2010Hex mobile phases. The thermally induced path\u2010dependant behaviors were caused by slow equilibration as evidenced by the disappearance of the hysteresis in the second heating to cooling cycle and in a cooling to heating cycle. From the step\u2010temperature program (10\u201350\u201310\u00b0C), only EtOH solvated AD and AS\u2010H phases showed the change of retention factors and\/or selectivities with time while only 2\u2010PrOH solvated AS\u2010H phase showed similar behaviors.<\/jats:p>","DOI":"10.1002\/jssc.200700388","type":"journal-article","created":{"date-parts":[[2008,2,12]],"date-time":"2008-02-12T07:16:55Z","timestamp":1202800615000},"page":"604-614","source":"Crossref","is-referenced-by-count":13,"title":["Column temperature programming in enantioseparation of dihydropyrimidinone compounds using derivatized cellulose and amylose chiral stationary phases"],"prefix":"10.1002","volume":"31","author":[{"given":"Fang","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Yeung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Semin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James S.","family":"McElvain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet","family":"Cheetham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,2,28]]},"reference":[{"key":"e_1_2_1_2_2","unstructured":"Li X. Hupp A. M. McGuffin V. L. in: Grushka E. Grinberg N. (Eds.) Advances in Chromatography CRC Press Boca Raton FL 2007."},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","unstructured":"Synder L. R. Kirkland J. J. Glajch J. L. Practical HPLC Method Development 2nd Edn. Wiley New York 1997.","DOI":"10.1002\/9781118592014"},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","unstructured":"Aboul\u2010Enein H. Y. Ali I. Chiral Separations by Liquid Chromatography and Related Technologies Marcel Dekker New York 2003.","DOI":"10.1201\/9780203911112"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9673(91)80106-Q"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac00185a019"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/jhrc.1240160505"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac961241l"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1081\/JLC-100101834"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(02)00404-1"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac00037a004"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac034714e"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2004.02.035"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2006.07.021"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(00)00862-1"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(99)00733-5"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(02)01735-1"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2005.03.073"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac0103672"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(03)01262-7"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-3773(19980504)37:8<1020::AID-ANIE1020>3.0.CO;2-5"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/chromsci\/19.4.195"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(01)94181-0"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(01)96759-7"}],"container-title":["Journal of Separation Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjssc.200700388","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jssc.200700388","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T13:27:12Z","timestamp":1760880432000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/jssc.200700388"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2,28]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,3]]}},"alternative-id":["10.1002\/jssc.200700388"],"URL":"https:\/\/doi.org\/10.1002\/jssc.200700388","archive":["Portico"],"relation":{},"ISSN":["1615-9306","1615-9314"],"issn-type":[{"type":"print","value":"1615-9306"},{"type":"electronic","value":"1615-9314"}],"subject":[],"published":{"date-parts":[[2008,2,28]]}}}