{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T10:26:34Z","timestamp":1789381594604,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2009,3,5]],"date-time":"2009-03-05T00:00:00Z","timestamp":1236211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Separation Science"],"published-print":{"date-parts":[[2009,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>An open tubular molecule imprinted polymer (OT\u2010MIP) capillary column has been prepared for chiral separation of ofloxacin enantiomers in CEC. The S\u2010ofloxacin imprinted OT column was fabricated by thermally initiated non\u2010covalent polymerization procedure inside a pretreated and silanized fused silica capillary. The template molecule was incorporated with methacrylic acid (MAA), ethylene glycol dimethacrylate (EDMA) and 4\u2010styrenesulfonic acid (4\u2010SSA) and dissolved in a porogen mixture of ACN\/2\u2010propanol (9:1). The separation efficiency of the 4\u2010SSA MIP column was found quite better than that of the MIP column without 4\u2010SSA. It has been demonstrated that our OT\u2010MIP column can separate ofloxacin enantiomers with excellent chiral separation efficiency after tuning the various chromatographic conditions. The optimized chromatographic eluent was 85:15, v\/v%, ACN\/60 mM sodium acetate at pH 7. The separation efficiency and selectivity of chiral separation of this study were far better than those obtained by previous methods for chiral separation of R\u2010 and S\u2010ofloxacin.<\/jats:p>","DOI":"10.1002\/jssc.200800631","type":"journal-article","created":{"date-parts":[[2009,3,5]],"date-time":"2009-03-05T10:30:51Z","timestamp":1236249051000},"page":"996-1001","source":"Crossref","is-referenced-by-count":39,"title":["Open tubular layer of S\u2010ofloxacin imprinted polymer fabricated in silica capillary for chiral CEC separation"],"prefix":"10.1002","volume":"32","author":[{"given":"Shabi Abbas","family":"Zaidi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoung Moon","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Soon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Guk","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won Jo","family":"Cheong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,3,19]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/37.1.7"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.31.4.582"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1875-9114.1988.tb04063.x"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.29.1.163"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-4347(88)80015-X"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(01)84609-4"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4347(99)00085-7"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0731-7085(96)01890-0"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2006.11.023"},{"key":"e_1_2_1_11_2","doi-asserted-by":"crossref","first-page":"2274","DOI":"10.1128\/AAC.41.10.2274","volume":"41","author":"Rabaa L.","year":"1997","journal-title":"Antimicrob. 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