{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:01:14Z","timestamp":1787166074086,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"22","license":[{"start":{"date-parts":[[2009,10,29]],"date-time":"2009-10-29T00:00:00Z","timestamp":1256774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Separation Science"],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A method has been developed to determine \u03b1, \u03b2 and \u03b3 diastereoisomers of hexabromocyclododecane (HBCD), a brominated flame retardant, in sewage sludge, based on the ultrasonic\u2010assisted extraction (UAE) of samples with dichloromethane\u2013ACN (1:1) and the subsequent clean\u2010up of extracts by dispersive solid phase extraction with primary\u2013secondary amine. Levels of HBCD diastereoisomers were determined by LC coupled with ESI MS\/MS. Evaluation of the matrix effect showed a high ion suppression for all the diastereoisomers studied, which was counteracted by using a mixture of labelled HBCD diastereoisomers as internal standards. This method yielded recoveries in the range of 79.6\u2013112.5% with SDs equal or lower than 9.1 The limits of detection were 0.3\u2009ng\/g for \u03b1\u2010 and \u03b2\u2010HBCD and 0.2\u2009ng\/g for \u03b3\u2010HBCD. The developed method was successfully applied to 19 sludge samples collected from the province of Madrid (Spain). In most of the samples, \u03b2\u2010HBCD was below the method detection limit, whereas \u03b1\u2010 and \u03b3\u2010HBCD were quantified in all of the sludge samples, and \u03b3\u2010HBCD was the predominant diastereoisomer in 63% of the analyzed samples and \u03b1\u2010HBCD predominated in the rest.<\/jats:p>","DOI":"10.1002\/jssc.200900424","type":"journal-article","created":{"date-parts":[[2009,10,29]],"date-time":"2009-10-29T17:08:34Z","timestamp":1256836114000},"page":"3890-3897","source":"Crossref","is-referenced-by-count":32,"title":["Determination of hexabromocyclododecane isomers in sewage sludge by LC\u2010MS\/MS"],"prefix":"10.1002","volume":"32","author":[{"given":"Ana Isabel","family":"Garc\u00eda\u2010Valc\u00e1rcel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luis","family":"Tadeo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,12,23]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2007.10.019"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2005.12.007"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2008.02.066"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2005.12.006"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0045-6535(03)00758-6"},{"key":"e_1_2_6_7_2","first-page":"389","volume":"57","author":"Eriksson P.","year":"2002","journal-title":"Organohalogen Compounds"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2005.04.043"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.1066"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1021\/es049640i"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/es0484909"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2008.02.082"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2004.11.024"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/es060009m"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2008.07.027"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2005.12.011"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.2116\/analsci.22.469"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/jaoac\/86.2.412"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.2129"},{"key":"e_1_2_6_20_2","first-page":"383","volume":"40","author":"Sellstr\u00f6m U.","year":"1999","journal-title":"Organohalogen Compd."},{"key":"e_1_2_6_21_2","first-page":"92","volume-title":"Advances in Organobromide Chemistry","author":"Peled M."},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1021\/es0602492"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2008.11.046"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2005.12.016"}],"container-title":["Journal of Separation Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjssc.200900424","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jssc.200900424","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T11:30:01Z","timestamp":1760873401000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/jssc.200900424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11]]},"references-count":23,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["10.1002\/jssc.200900424"],"URL":"https:\/\/doi.org\/10.1002\/jssc.200900424","archive":["Portico"],"relation":{},"ISSN":["1615-9306","1615-9314"],"issn-type":[{"value":"1615-9306","type":"print"},{"value":"1615-9314","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,11]]}}}