{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:26:20Z","timestamp":1791404780541,"version":"4.3.3"},"reference-count":26,"publisher":"Wiley","issue":"14","license":[{"start":{"date-parts":[[2011,6,24]],"date-time":"2011-06-24T00:00:00Z","timestamp":1308873600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Harvard-NIEHS Center for Environmental Health","award":["ES000002"],"award-info":[{"award-number":["ES000002"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Separation Science"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Bisphenol A (BPA) is one of the environmental endocrine\u2010disrupting chemicals used widely in common consumer products. There is an increasing concern about human exposure to BPA, particularly in fetuses, due to the potential adverse effects related to the estrogenic activity of BPA. In assessing environmental exposure to BPA, it is essential to have a sensitive, accurate, and specific analytical method, particularly for low BPA levels in complex sample matrices. In this study, we developed and validated an accurate, sensitive, and robust liquid chromatography\u2013mass spectrometry (LC\u2010MS) method for determining the BPA concentrations in human amniotic fluid (AF). In this method, BPA and the internal standards <jats:sup>13<\/jats:sup>C<jats:sub>12<\/jats:sub>\u2010BPA were extracted from 500\u2009\u03bcL of human AF using solid\u2010phase extraction. Calibration curves were linear over a concentration range of 0.3\u2013100\u2009ng\/mL for BPA. The analytes were quantitatively determined using LC\u2010MS operated in a negative electrospray ionization selected ion monitoring mode. This validated method has been used successfully in the clinical sample analysis of BPA in second\u2010trimester AF specimens.<\/jats:p>","DOI":"10.1002\/jssc.201100152","type":"journal-article","created":{"date-parts":[[2011,6,30]],"date-time":"2011-06-30T06:26:09Z","timestamp":1309415169000},"page":"1648-1655","source":"Crossref","is-referenced-by-count":44,"title":["Determination of bisphenol\u2010A levels in human amniotic fluid samples by liquid chromatography coupled with mass spectrometry"],"prefix":"10.1002","volume":"34","author":[{"given":"Mei","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea G.","family":"Edlow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole A.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas F.","family":"McElrath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chensheng","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,6,24]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.publhealth.012809.103714"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.0901716"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.10753"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/17.11.2839"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2006.0185"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.021100703"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/44517"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1998.tb01314.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2008.09.015"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.01.025"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.5603"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-199936060-00005"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.0900979"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0890-6238(02)00051-5"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0731-7085(02)00516-2"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4347(99)00471-5"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1080\/15376520600697404"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2005.07.007"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.105.005454"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00244-002-2124-0"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.3307"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac050390d"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/jat\/12.4.236"},{"key":"e_1_2_6_25_2","first-page":"878","volume":"15","author":"Verplaetse R.","year":"2010","journal-title":"J. Chromatogr. B"},{"key":"e_1_2_6_26_2","first-page":"11","volume":"75","author":"Modena A. B.","year":"2004","journal-title":"Acta Biomed."},{"key":"e_1_2_6_27_2","volume-title":"Quality Assurance of Chemical Measurements","author":"Tayor J. K.","year":"1987"}],"container-title":["Journal of Separation Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjssc.201100152","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjssc.201100152","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jssc.201100152","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T14:14:03Z","timestamp":1760883243000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/jssc.201100152"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6,24]]},"references-count":26,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["10.1002\/jssc.201100152"],"URL":"https:\/\/doi.org\/10.1002\/jssc.201100152","archive":["Portico"],"relation":{},"ISSN":["1615-9306","1615-9314"],"issn-type":[{"value":"1615-9306","type":"print"},{"value":"1615-9314","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,6,24]]}}}