{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T03:02:23Z","timestamp":1785294143870,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","issue":"19","license":[{"start":{"date-parts":[[2012,9,3]],"date-time":"2012-09-03T00:00:00Z","timestamp":1346630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Greek national funds"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Separation Science"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:p>The application of ultrasound\u2010assisted matrix solid phase dispersive extraction for the confirmatory analysis of 12 \u03b2\u2010lactam antibiotics in milk by high performance liquid chromatography with photodiode array detection has been proposed herein. Four penicillins (cloxacillin, dicloxacillin, oxacillin, and amoxicillin) and eight cephalosporins (cefaclor, cefadroxil, ceftiofur, cefuroxime, cefoperazone, cefazolin, cephalexin, and cefotaxime) are effectively extracted using a mixed sorbent of Quick Easy Cheap Effective Rugged Safe technique and <jats:styled-content style=\"fixed-case\">OASIS HLB<\/jats:styled-content> providing a matrix free from any endogenous interference. Examined analytes were well resolved on an Inertsil <jats:styled-content style=\"fixed-case\">ODS<\/jats:styled-content>\u20103 analytical column with a mobile phase of <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content><jats:sub>3<\/jats:sub><jats:styled-content style=\"fixed-case\">COONH<\/jats:styled-content><jats:sub>4<\/jats:sub> (0.05 M) and acetonitrile delivered under a gradient program. 1,7\u2010Dimethyl\u2010xanthine was used as internal standard. The method was validated meeting the <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>uropean <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>egislation determining linearity, selectivity, stability, decision limit, detection capability, accuracy, precision, and ruggedness according to the <jats:styled-content style=\"fixed-case\">Y<\/jats:styled-content>ouden approach. Recoveries of all antibiotics rated from 85.0 to 115.7%, while <jats:styled-content style=\"fixed-case\">RSD<\/jats:styled-content> values were &lt;12.7%. Finally, the method was successfully applied to milk samples purchased from local market.<\/jats:p>","DOI":"10.1002\/jssc.201200514","type":"journal-article","created":{"date-parts":[[2012,9,3]],"date-time":"2012-09-03T06:07:04Z","timestamp":1346652424000},"page":"2599-2607","source":"Crossref","is-referenced-by-count":49,"title":["Ultrasound\u2010assisted matrix solid phase dispersive extraction for the simultaneous analysis of \u03b2\u2010lactams (four penicillins and eight cephalosporins) in milk by high performance liquid chromatography with photodiode array detection"],"prefix":"10.1002","volume":"35","author":[{"given":"Eftichia G.","family":"Karageorgou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria F.","family":"Samanidou","sequence":"additional","affiliation":[{"name":"Laboratory of Analytical Chemistry Department of Chemistry Aristotle University of Thessaloniki  Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis N.","family":"Papadoyannis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,9,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/0265203031000098696"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2008.01.037"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-006-0929-9"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2007.04.027"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf0344284"},{"key":"e_1_2_7_7_1","first-page":"8","volume":"221","year":"2002","journal-title":"Off. 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