{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T09:02:07Z","timestamp":1777539727826,"version":"3.51.4"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,2,4]],"date-time":"2013-02-04T00:00:00Z","timestamp":1359936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Separation Science"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:p>In the present study, a convenient and sensitive method for determination of six penicillin antibiotics (amoxicillin, ampicillin, penicillin <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>, oxacillin, cloxacillin, and dicloxacillin) in milk and honey samples was developed. Milk and honey samples were diluted with water, then directly treated by stir bar sorptive extraction based on poly (vinylimidazole\u2010divinylbenzene) monolithic material as coating. The analytes were analyzed by <jats:styled-content style=\"fixed-case\">LC\/ESI\u2010 MS\/MS<\/jats:styled-content>. Several extraction parameters including extraction and desorption time, p<jats:styled-content style=\"fixed-case\">H<\/jats:styled-content> value, and ionic strength in sample matrix were investigated in detail. Under the optimized extraction conditions, the calculated detection limits for the target compounds were as low as 0.23\u20132.66 ng\/kg in milk and 0.18\u20131.42 ng\/kg in honey, respectively. Good linearity was obtained for analytes with the correlation coefficients (<jats:italic><jats:styled-content style=\"fixed-case\">R<\/jats:styled-content><\/jats:italic><jats:sup>2<\/jats:sup>) above 0.997. Excellent method reproducibility was achieved in terms of intraday and interday precisions, indicated by the <jats:styled-content style=\"fixed-case\">RSD<\/jats:styled-content>s of &lt;5.0 and &lt;10.0%, respectively. Finally, the proposed method was successfully applied to the determination of penicillin antibiotics residues in different milk and honey samples.<\/jats:p>","DOI":"10.1002\/jssc.201200987","type":"journal-article","created":{"date-parts":[[2012,11,26]],"date-time":"2012-11-26T11:23:27Z","timestamp":1353929007000},"page":"907-915","source":"Crossref","is-referenced-by-count":24,"title":["Sensitive monitoring of penicillin antibiotics in milk and honey treated by stir bar sorptive extraction based on monolith and <scp>LC<\/scp>\u2010electrospray <scp>MS<\/scp> detection"],"prefix":"10.1002","volume":"36","author":[{"given":"Xiaojia","family":"Huang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Marine Environmental Science Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystem College of the Environment and Ecology Xiamen University  Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linli","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Marine Environmental Science Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystem College of the Environment and Ecology Xiamen University  Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Marine Environmental Science Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystem College of the Environment and Ecology Xiamen University  Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongxing","family":"Yuan","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Marine Environmental Science Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystem College of the Environment and Ecology Xiamen University  Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuyu","family":"Nong","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Marine Environmental Science Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystem College of the Environment and Ecology Xiamen University  Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,2,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2005.09.056"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf0499572"},{"key":"e_1_2_7_4_1","first-page":"1","volume":"224","author":"European Commission, Council Regulation (EEC) 2377\/90\/EC","year":"1990","journal-title":"Off. J. Eur. Commun."},{"key":"e_1_2_7_5_1","first-page":"8","volume":"73","author":"European Commission, Commission Regulation (EEC) 92\/675\/EC","year":"1992","journal-title":"Off. J. Eur. Commun."},{"key":"e_1_2_7_6_1","first-page":"64","volume":"118","author":"European Commission, Council Regulation (EEC) 93\/256\/EC","year":"1993","journal-title":"Off. J. Eur. Commun."},{"key":"e_1_2_7_7_1","unstructured":"The maximum residue limit of veterinary drugs in edible animal food established by Ministry of Agriculture of People's Republic of China No. 235 2002 pp.7\u201310."},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2008.10.058"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0956-7135(98)00154-6"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf071479i"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/108705710200700205"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540100120075817"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-008-2106-9"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2011.01.016"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-012-5868-z"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2009.04.005"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/19440049.2011.604044"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.200900212"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac0011383"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1520-667X(1999)11:10<737::AID-MCS7>3.0.CO;2-4"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2008.08.103"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2009.03.043"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.329"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02491731"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(00)00836-0"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0231(19981230)12:24<2031::AID-RCM432>3.0.CO;2-8"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf010994s"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0103-50532007000200023"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.3532"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2011.01.016"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002160100858"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2006.05.049"}],"container-title":["Journal of Separation Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjssc.201200987","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jssc.201200987","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T08:47:36Z","timestamp":1760863656000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/jssc.201200987"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,4]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["10.1002\/jssc.201200987"],"URL":"https:\/\/doi.org\/10.1002\/jssc.201200987","archive":["Portico"],"relation":{},"ISSN":["1615-9306","1615-9314"],"issn-type":[{"value":"1615-9306","type":"print"},{"value":"1615-9314","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,4]]}}}