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The increasing concern of the fate of these compounds into the environment has led to the development of analytical methods to determine them. However, these methods present problems due to the polar character of these analytes. In this paper, hydrophilic interaction LC is presented as an alternative technique. The retention of iodinated X\u2010ray contrast media was studied in two bare silica phases with different particle designs (i.e. porous and Fused Core\u2122) and a zwitterionic sulfoalkylbetaine phase. The effect of the most important parameters of the mobile phase was studied for each stationary phase. It was observed that optimal mobile phase conditions included buffers with a high buffering capacity. Additionally, the retention mechanisms involved were studied in order to provide some insight into the possible occurring interactions. The contributions of partition and adsorption and the effect of the temperature on the retention of analytes were evaluated on all of the stationary phases.<\/jats:p>","DOI":"10.1002\/jssc.201301231","type":"journal-article","created":{"date-parts":[[2014,2,24]],"date-time":"2014-02-24T12:54:55Z","timestamp":1393246495000},"page":"1111-1117","source":"Crossref","is-referenced-by-count":2,"title":["Study of the retention behavior of iodinated X\u2010ray contrast agents in hydrophilic interaction liquid chromatography, comparing bare silica and zwitterionic stationary phases"],"prefix":"10.1002","volume":"37","author":[{"given":"Daniela","family":"Salas","sequence":"first","affiliation":[{"name":"Department of Analytical Chemistry and Organic Chemistry Universitat Rovira i Virgili  Tarragona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesc","family":"Borrull","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry and Organic 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