{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T11:16:34Z","timestamp":1790334994745,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2015,5,7]],"date-time":"2015-05-07T00:00:00Z","timestamp":1430956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21277100"],"award-info":[{"award-number":["21277100"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Separation Science"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:p>A highly sensitive method based on solid\u2010phase extraction and ultra high performance liquid chromatography with electrospray tandem mass spectrometry has been developed for simultaneous determination of five iodinated X\u2010ray contrast media in environmental water samples. Various solid\u2010phase extraction cartridges have been evaluated and a combination of LiChrolute EN and ENVI\u2010Carb solid phase extraction cartridges was selected for sample enrichment. The method was comprehensively validated on ground water, tap water, surface water, drinking water, and waste water by the conventional procedures: linearity, method detection limits, accuracy and precision, matrix effects. Good linearity (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> &gt; 0.999), low detection limits (0.4\u20138.1 ng\/L), satisfactory recoveries (55.1\u2013109.5%) and precision (0.8\u201310.0% for intra\u2010day precisions and 0.6\u201316.5% for inter\u2010day precisions) were obtained for all the target compounds. Iopamidol, iohexol, and diatrizoate in some matrices were affected by matrix effects, which were slightly eased by using the isotope\u2010labeled internal standard. The developed method was successfully applied for real samples collected in Shanghai, China, with detected concentrations up to 2200 \u00b1 200 and 9000 \u00b1 1000 ng\/L for iohexol and iopamidol, respectively.<\/jats:p>","DOI":"10.1002\/jssc.201401296","type":"journal-article","created":{"date-parts":[[2015,4,2]],"date-time":"2015-04-02T17:59:55Z","timestamp":1427997595000},"page":"1998-2005","source":"Crossref","is-referenced-by-count":22,"title":["Solid\u2010phase extraction coupled with ultra high performance liquid chromatography and electrospray tandem mass spectrometry for the highly sensitive determination of five iodinated X\u2010ray contrast media in environmental water samples"],"prefix":"10.1002","volume":"38","author":[{"given":"Xia","family":"Li","sequence":"first","affiliation":[{"name":"State Key Laboratory of Pollution Control and Resources Reuse College of Environmental Science and Engineering Tongji University  Shanghai P.R. 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