{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:22:55Z","timestamp":1760919775110,"version":"build-2065373602"},"reference-count":23,"publisher":"Wiley","issue":"20","license":[{"start":{"date-parts":[[2015,9,9]],"date-time":"2015-09-09T00:00:00Z","timestamp":1441756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Separation Science"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:p>The aim of this study was the evaluation of the binding performances and selectivity of molecularly imprinted beads prepared toward several penicillins (i) by hierarchical bulk polymerization in the pores of template\u2010grafted silica microbeads (hMIPs) and (ii) by Pickering emulsion polymerization in the presence of template\u2010decorated silica nanobeads (pMIPs). 6\u2010Aminopenicillanic acid was chosen as the common fragmental mimic template. Both approaches produced micron\u2010sized polymeric beads with good recognition properties toward the target ligands whereas the selectivity pattern appeared quite different. The polymer prepared by the Pickering emulsion approach showed binding properties similar to imprinted beads prepared by hierarchical approach. Equilibrium binding constants changed their values from 0.1\u20130.2 \u00d7 10<jats:sup>6<\/jats:sup> (hMIPs) to 0.2\u20130.6 \u00d7 10<jats:sup>6<\/jats:sup> M<jats:sup>\u22121<\/jats:sup> (pMIPs), while the binding site densities changed from 3.7\u20134.8 (hMIPs) to 0.3\u20130.55 \u03bcmol\/g (pMIPs). Compared to the hierarchical polymerization, Pickering emulsion polymerization represents a more practical approach when a template mimic needs to be used.<\/jats:p>","DOI":"10.1002\/jssc.201500511","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T05:55:13Z","timestamp":1438926913000},"page":"3661-3668","source":"Crossref","is-referenced-by-count":9,"title":["Comparison of binding behavior for molecularly imprinted polymers prepared by hierarchical imprinting or Pickering emulsion polymerization"],"prefix":"10.1002","volume":"38","author":[{"given":"Cristina","family":"Giovannoli","sequence":"first","affiliation":[{"name":"Department of Chemistry University of Torino  via Giuria 5 Torino Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cinzia","family":"Passini","sequence":"additional","affiliation":[{"name":"Department of Chemistry University of Torino  via Giuria 5 Torino 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