{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T09:39:19Z","timestamp":1790069959890,"version":"4.0.1"},"reference-count":34,"publisher":"Wiley","issue":"18","license":[{"start":{"date-parts":[[2017,8,28]],"date-time":"2017-08-28T00:00:00Z","timestamp":1503878400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Separation Science"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We present an environmentally friendly method for the analysis of three angiotensin\u2010converting enzyme inhibitors and hydrochlorothiazide simultaneously using a green micellar eluent for the first time. The chromatographic separation of enalapril maleate, lisinopril dihydrate, benazepril hydrochloride, and hydrochlorothiazide was implemented on an octadecyl silica column with a solution containing sodium dodecyl sulfate (0.12\u00a0M), 1\u2010propyl alcohol (10% v\/v), triethylamine (0.3% v\/v), and H<jats:sub>3<\/jats:sub>PO<jats:sub>4<\/jats:sub> (0.02\u00a0M) at pH 3.6 as the mobile phase and UV detection at 210\u00a0nm. Validity of the method was confirmed and it exhibited good linearity within the ranges of 5.0\u201350.0\u00a0\u03bcg\/mL for hydrochlorothiazide and 10.0\u201360.0\u00a0\u03bcg\/mL for the three angiotensin\u2010converting enzyme inhibitors with a limit of detection of 0.39 to 1.15\u00a0\u03bcg\/mL for all the studied drugs. The developed micellar high\u2010performance liquid chromatography method enables the quantification of the targeted angiotensin\u2010converting enzyme inhibitors in combined tablets with hydrochlorothiazide by isocratic elution. There is no need for special precautions to prevent broadening and splitting of their chromatographic peaks. The method fulfills the society rights for safe and green analytical methods. The retention behavior of the four studied drugs was fitted to Foley's model and their association equilibria to the micelles (<jats:italic>K<\/jats:italic><jats:sub>AM<\/jats:sub>) and to the surface\u2010modified stationary phase (<jats:italic>K<\/jats:italic><jats:sub>AS<\/jats:sub>) were calculated.<\/jats:p>","DOI":"10.1002\/jssc.201700622","type":"journal-article","created":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T08:25:42Z","timestamp":1500452742000},"page":"3646-3654","source":"Crossref","is-referenced-by-count":14,"title":["Green micellar HPLC analysis of three angiotensin\u2010converting enzyme inhibitors in their mixtures with hydrochlorothiazide and modeling of their retention behavior by fitting to <b>Foley's<\/b> model"],"prefix":"10.1002","volume":"40","author":[{"given":"Manal","family":"Eid","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy Mansoura University  Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasser","family":"El\u2010Shabrawy","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy Mansoura University  Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8830-4222","authenticated-orcid":false,"given":"Rania","family":"El\u2010Shaheny","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy Mansoura University  Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,28]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"36","volume-title":"Martindale: The Complete Drug Reference","author":"Sweetman S. 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