{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T17:30:26Z","timestamp":1783618226387,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T00:00:00Z","timestamp":1675900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Separation Science"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:p>A simple and rapid high\u2010performance thin\u2010layer chromatographic method for quantification of gallic acid and ellagic acid in dried fruits of <jats:italic>Terminalia chebula<\/jats:italic>, <jats:italic>Phyllanthus emblica<\/jats:italic>, and <jats:italic>Quercus infectoria<\/jats:italic> has been developed. The chromatographic development was carried out on precoated silica gel 60 F<jats:sub>254<\/jats:sub> plates in a mixture of toluene:ethyl acetate:chloroform:formic acid (4:8:1:3 v\/v\/v\/v). The plate was scanned densitometrically at a wavelength of 280\u00a0nm. The retention factor value of gallic acid and ellagic acid was found to be 0.63\u00a0\u00b1\u00a00.2 and 0.53\u00a0\u00b1\u00a00.1, respectively. The developed method was validated in terms of linearity, precision, accuracy, sensitivity, robustness, specificity and stability as per the international conference of harmonization guidelines. The method showed good linear relationship over a range of 100\u2013600\u00a0ng\/band (gallic acid) and 100\u2013500\u00a0ng\/band (ellagic acid) with a regression coefficient (<jats:italic>r<\/jats:italic><jats:sup>2<\/jats:sup>) of 0.997 (gallic acid) and 0.996 (ellagic acid). The method showed high accuracy (99.65%\u2013100.85%). The percentage relative standard deviation of intra\u2010day and inter\u2010day precision studies was not more than 2%. The method is highly robust and has displayed high specificity. The developed method is new, simple, and accurate and can be successfully employed in routine analysis of raw materials and formulations containing gallic acid and ellagic acid.<\/jats:p>","DOI":"10.1002\/jssc.202200991","type":"journal-article","created":{"date-parts":[[2023,1,15]],"date-time":"2023-01-15T01:24:03Z","timestamp":1673745843000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Validated high\u2010performance thin\u2010layer chromatographic method for quantification of gallic acid and ellagic acid in fruits of <i>Terminalia<\/i><i>chebula<\/i>, <i>Phyllanthus<\/i><i>embli<\/i><i>ca<\/i>, and <i>Quercus<\/i><i>infectoria<\/i>"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3972-1764","authenticated-orcid":false,"given":"Shilpa","family":"Godiyal","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Sciences and Technology Medicinal Natural Products Research Laboratory (MNPRL), Institute of Chemical Technology  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirti","family":"Laddha","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences and Technology Medicinal Natural Products Research Laboratory (MNPRL), Institute of Chemical Technology  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.6702"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.23880\/ipcm\u201016000208"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf950238k"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0250\u2010474X.57286"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2221\u20101691(13)60059\u20103"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2016.06.013"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.20959\/wjpps20194\u201013486"},{"key":"e_1_2_9_9_1","first-page":"105","article-title":"Ethnopharmacology of quercus infectoria galls: a review","volume":"11","author":"Ansari Shaiqua AH","year":"2016","journal-title":"Hippocratic J Unani Med"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2221\u20101691(14)60205\u20107"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.22038\/ijbms.2019.32806.7897"},{"key":"e_1_2_9_12_1","first-page":"132","article-title":"Gallic acid: pharmacogical promising lead molecule: a review","volume":"10","author":"Singh PM","year":"2018","journal-title":"Int J Pharmacog Phytochem Res"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.30574\/gscbps.2020.13.1.0311"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpha.2020.07.010"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1134\/S1061934813120113"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2006.11.061"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1515\/revac\u20102020\u20100113"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/chromsci\/bmu096"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13197\u2010019\u201003716\u20107"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/10826076.2011.636468"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.4103\/2229\u20104708.84436"},{"key":"e_1_2_9_22_1","unstructured":"International Council for Harmonisation.Harmonised tripartite guideline. 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