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It is mainly used in treating vitiligo, with the effect of activating pulse\u2010beat and regulating blood condition. However, the chemical composition of QBBBQT has not been reported, and it was difficult to determine its active and toxic components. In this study, a simple and efficient method was established to characterize the chemical constituents of the alcohol extract of QBBBQT. Which used ultra\u2010high\u2010performance liquid chromatography quadrupole\u2010orbitrap\u2010mass spectrometry to match experimental MS\n                    <jats:sup>2<\/jats:sup>\n                    with characteristic ions and neutral losses for rapid analysis and identification of its chemical composition. Finally, a total of 106 chemical components were identified, including 47 flavonoids, 13 coumarins, 21 organic acids, 11 diarylheptanes, four saccharides, and 10 others. This method can be used for the systematic and rapid analysis of the chemical components in QBBBQT, which is of great significance for the study of its pharmacodynamic material basis and quality control.\n                  <\/jats:p>","DOI":"10.1002\/jssc.70117","type":"journal-article","created":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T07:41:50Z","timestamp":1747899710000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Rapid Identification of Chemical Constituents in Qubai Babuqi Tablets by Ultra\u2010High\u2010Performance Liquid Chromatography Quadrupole\u2010Orbitrap\u2010Mass Spectrometry"],"prefix":"10.1002","volume":"48","author":[{"given":"Xuebin","family":"Qin","sequence":"first","affiliation":[{"name":"School of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiahui","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lulu","family":"Yu","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miao","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siyue","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yajie","family":"Dou","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangzhi","family":"Cui","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuming","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanyan","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0455-0969","authenticated-orcid":false,"given":"Yubo","family":"Li","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,22]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"637","article-title":"Effect Observation of Qubai Babuqi Pian Combined With Tacrolimus Ointment in the Treatment of Vitiligo","volume":"34","author":"Wang Y. 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