{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T04:46:54Z","timestamp":1783745214110,"version":"3.55.0"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T00:00:00Z","timestamp":1748217600000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Separation Science"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    A straightforward and practical 15\u2010min gas chromatographic method utilizing flame ionization detection has been developed to measure hydrogen cyanide in various matrices. This new approach features a catalyzed two\u2010stage post\u2010column reaction that significantly enhances the detection and quantification of hydrogen cyanide. Selecting the right separation column is crucial for accurate analysis. Initial tests with porous layer open tubular columns resulted in significant peak tailing, rendering them unsuitable for trace\u2010level analysis. Modified polyethylene glycol stationary phases also exhibited strong peak tailing in addition to producing artifact peaks. In contrast, a polydimethylsiloxane\u2010based column with a very low phase ratio (\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \u00a0=\u00a010) demonstrated excellent analytical performance, including peak symmetry and inertness. The analytical approach achieved a minimum detection limit of 50 parts per billion (ppb, v\/v) without preconcentration and a linear range from 0.05 to 200 parts per million (ppm, v\/v). At a concentration level of 20\u00a0ppm (v\/v), the RSD at the 95% confidence level was less than 1% (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a010), and at a concentration level of 1\u00a0ppm (v\/v), the RSD at the 95% confidence level was less than 3% (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a010) under the established conditions. The method's effectiveness has been validated through real\u2010life applications, including analyzing hydrogen cyanide in fruit seeds and the headspace of untreated water samples.\n                  <\/jats:p>","DOI":"10.1002\/jssc.70176","type":"journal-article","created":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T00:59:59Z","timestamp":1748307599000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Determination of Hydrogen Cyanide by Gas Chromatography With Post\u2010Column Reaction and Flame Ionization Detection"],"prefix":"10.1002","volume":"48","author":[{"given":"Ronda","family":"Gras","sequence":"first","affiliation":[{"name":"Dow Canada ULC  Fort Saskatchewan Alberta Canada"},{"name":"Australian Centre for Research on Separation Science (ACROSS) University of Tasmania  Tasmania Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4120-1207","authenticated-orcid":false,"given":"Jim","family":"Luong","sequence":"additional","affiliation":[{"name":"Dow Canada ULC  Fort Saskatchewan Alberta Canada"},{"name":"Australian Centre for Research on Separation Science (ACROSS) University of Tasmania  Tasmania Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Shellie","sequence":"additional","affiliation":[{"name":"Centre for Food Safety and Innovation, Tasmanian Institute of Agriculture University of Tasmania  Tasmania Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2018.01.320"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0196\u20100644(86)80131\u20107"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mineng.2018.07.005"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atmosenv.2005.09.089"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jafrearsci.2017.04.023"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2014.08.083"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1466\u20108564(99)00004\u20101"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/096032719201100107"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168\u20101605(94)00115\u2010m"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2006.10.071"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.enzmictec.2006.05.004"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u20103054.1991.tb00114.x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3109\/15563658408992565"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/156482650202300418"},{"key":"e_1_2_9_16_1","volume-title":"Combustion Toxicology: Principles and Test Methods","author":"Kaplan H. L.","year":"1983"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0041\u2010008x(81)90278\u20107"},{"key":"e_1_2_9_18_1","first-page":"99","article-title":"Analysis of Hydrogen Cyanide in Fire Environments","volume":"6","author":"Paabo M.","year":"1979","journal-title":"Journal of Combustion Toxicology"},{"key":"e_1_2_9_19_1","volume-title":"The Combustion of Organic Polymers","author":"Cullis C. F.","year":"1981"},{"key":"e_1_2_9_20_1","unstructured":"The National Institute for Occupational Safety and Health(NIOSH) \u201cEmergency Response Safety and Health Database \u201d2011 https:\/\/www.cdc.gov\/niosh\/ershdb\/emergencyresponsecard_29750038.html."},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apr.2016.12.013"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/jaoac\/93.3.1032"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2014.08.009"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2010.05.042"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sab.2008.10.042"},{"issue":"12","key":"e_1_2_9_26_1","first-page":"1262","article-title":"The Flame Ionization Detector","volume":"23","author":"Hinshaw J. V.","year":"2005","journal-title":"LCGC North America"},{"issue":"6","key":"e_1_2_9_27_1","first-page":"7","article-title":"Enhancing Flame Ionization Detector Capabilities With Post\u2010Column Reaction","volume":"39","author":"Luong J.","year":"2021","journal-title":"Hot Topics in Gas Chromatography"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2019.460460"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.9b02159"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1039\/c8ay02414f"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5AN02552D"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.201800383"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/9783527614752"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/jhrc.1240190106"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165\u20109936(02)00809\u20109"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.56530\/lcgc.int.zn9272e9"}],"container-title":["Journal of Separation Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jssc.70176","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jssc.70176","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jssc.70176","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T08:44:15Z","timestamp":1769589855000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/jssc.70176"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1002\/jssc.70176"],"URL":"https:\/\/doi.org\/10.1002\/jssc.70176","archive":["Portico"],"relation":{},"ISSN":["1615-9306","1615-9314"],"issn-type":[{"value":"1615-9306","type":"print"},{"value":"1615-9314","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"2025-02-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70176"}}